Zentel Susp 10ml

What it is used for: Parasitic Infection.

Indications as listed by the manufacturer: It is indicated in the treatment of single or mixed intestinal parasites. Clinical studies have shown albendazole effective in the treatment of Ascaris lumbricoides (roundworm), Trichuris trichiura (whipworm), Enterobius vermicularis (pinworm/threadworm), Ancylostoma duodenale and Necator americanus (hookworm), Taenia spp. (tapeworm) and Strongyloides stercoralis. It has been shown to be effective in the treatment of Giardia (duodenalis or intestinalis or lamblia) infections in children.

How it works: Albendazole is a benzimidazole carbamate with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. Animal studies have shown that albendazole exhibits vermicidal, ovacidal and larvacidal activity and exerts its anthelmintic effect by inhibiting tubulin polymerisation. This causes the disruption of the helminth metabolism, including energy depletion, which immobilises and then kills the susceptible helminth.

Active ingredient: Albendazole.

Reported side effects: GI disturbances , headache , dizziness , rash , fever , rarely reversible alopecia , haematological and liver enzyme changes.

Known drug interactions: Praziquantel increases the plasma levels of the active metabolite of medicine. Ritonavir, phenytoin, carbamazepine and phenobarbital may reduce plasma concentrations of the active metabolite of the medicine; albendazole sulfoxide. The clinical relevance of this is unknown, but may result in decreased efficacy, especially in the treatment of systemic helminth infections. Patients should be monitored for efficacy and may require alternative dose regimens or therapies.

Usual Dose: 400 mg (two Albendazole 200 mg tablets) or 20 ml (400 mg) of Albendazole suspension as a single dose in both adults and children over two years of age. The usual dose in children between one and two years of age is 10 ml (200 mg) of Albendazole suspension as a single dose. In heavy mixed infestation involving Strongyloides or Taeniasis, a single daily dose may be inadequate and the dose may be given for three consecutive days. OR As directed by your physician.

Active ingredient: Albendazole. Labelled strength: 100mg/5ml.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Zentel Pharmaceuticals (Pvt) Ltd.. Country of origin: Germany.