Losar plus Tablets 5012/5mg 2x10s

What it is used for: Hypertension.

Indications as listed by the manufacturer: It is indicated for the treatment of Hypertension.

How it works: It is a combination of an angiotensin II receptor antagonist (losartan) and a diuretic (hydrochlorothiazide). Angiotensin II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Losartan prevents the binding of angiotensin II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Hydrochlorothiazide works by making the kidneys pass more water and salt. This also helps to reduce blood pressure.

Active ingredient: Losartan Potassium , Hydrochlorothiazide.

Reported side effects: Cough, upper airway infection, congestion in the nose, sinusitis, sinus disorder , Diarrhoea, abdominal pain, nausea, indigestion , Muscle pain or cramps, leg pain, back pain , Insomnia, headache, dizziness , Weakness, tiredness, chest pain , Increased potassium levels (which can cause an abnormal heart rhythm), decreased haemoglobin levels , Changes in kidney function including kidney failure , Low blood sugar (hypoglycaemia) , Loss of appetite, increased uric acid levels or frank gout, increased blood sugar levels, abnormal blood electrolyte levels , Anxiety, nervousness, panic disorder (recurring panic attacks), confusion, depression, abnormal dreams, sleep disorders, sleepiness, memory impairment.

Known drug interactions: Trimethoprim , Diuretic agents , other medicines to reduce your blood pressure , steroids , medicines to treat cancer , painkillers , drugs for treatment of infections, including fungal infections , arthritis medicines , resins used for high cholesterol, such as colestyramine , medicines which relax your muscles , sleeping tablets , opioid medicines such as morphine , “pressor amines” such as adrenaline or other drugs from the same group , oral agents for diabetes or insulins , anticholinergic agents (e.g. atropine, biperiden) , antipsychotics , antidepressants , carbamazepine.

Adults : The recommended usual dose 1 tablet per day to control blood pressure over the 24-hour period. This can be increased to 2 tablets once daily of film-coated tablets or changed to 1 tablet daily of 100mg/25mg film-coated tablets (a stronger strength) per day. The maximum daily dose is 2 tablets per day of 50mg/12.5mg film-coated tablets or 1 tablet daily of 100mg/25mg film-coated tablets. Children : Not recommended . Check with your doctor or pharmacist if you are not sure.

Active ingredient: Losartan Potassium , Hydrochlorothiazide. Labelled strength: 50mg/12.5mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Losar Laboratories (Pvt) Ltd.. Country of origin: Pakistan.