Xantix 2mg Tablets 10s

What it is used for: Muscle Spasm.

Indications as listed by the manufacturer: Painful muscle spasms: Associated with static and functional disorders of the spine (cervical and lumber syndromes). Following surgery, e.g. for herniated intervertebral disc or osteoarthritis of the hip. Spasticity due to neurological disorders: Eg. multiple sclerosis, chronic myelopathy, degenerative spinal cord diseases, cerebrovascular accidents, and cerebral palsy.

How it works: Tizanidine is a centrally acting skeletal muscle relaxant. Its principal site of action is the spinal cord, where the evidence suggests that, by stimulating presynaptic alpha2-receptors, it inhibits the release of excitatory aminoacids that simulate N-methyl-D-aspartate (NMDA) receptors. Polysynaptic signal transmission at spinal interneuron level, which is responsible for excessive muscle tone, is thus inhibited and muscle tone reduced.

Active ingredient: Tizanidine.

Reported side effects: Psychiatric disorders: Rare: Hallucination, insomnia, sleep disorder . Nervous system disorders: Common: Bradycardia . Vascular disorders - Common: Hypotension . Gastrointestinal disorders Common: Dry mouthRare:Nausea, gastrointestinal disorder Hepatobiliary disorders: Very rare: Hepatitis Musculoskeletal and connective tissue disorders Rare: Muscular weakness General disorders and administration site conditions Common: Fatigue.

Known drug interactions: Fluvoxamine or ciprofloxacin, CYP4501A2 inhibitors , antiarrhythmics (amiodarone, mexiletine, propafenone) cimetidine, some fluoroquinolones ( enoxacin, pefloxacin, norfloxacin) rofecoxaib, oral contraceptives and ticlopidine , Alcohol and sedatives.

Relief of painful muscle spasms: 2 to 4 mg three times daily in tablet form. In severe cases an extra dose of 2 or 4 mg may be taken at night. Spasticity due to neurological disorders: The dosage should be adjusted to the needs of the individual patient. The initial daily dose should not exceed 6 mg given in 3 divided doses. It may be increased stepwise at half weekly or weekly intervals by 2-4mg. The optimum therapeutic response is generally achieved with at daily dose of between 12 & 24mg, administrated in 3 to 4 divided doses. The total daily dose should not exceed 36 mg. Children: Its use in children is not recommended.

Active ingredient: Tizanidine. Labelled strength: 2mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Xantix Healthcare (Pvt) Ltd.. Country of origin: Germany.