Lornex 8mg 20 Tablets

What it is used for: Pain & Inflammation.

Indications as listed by the manufacturer: Lornoxicam is indicated for: Short term treatment of moderate pain, such as pain after dental surgery. - Short term treatment of mild to moderate pain associated with extra articular inflammation. - Treatment of pain associated with acute lumbo-sciatica. - Symptomatic treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis.

How it works: The mode of action of lornoxicam is partly based on inhibition of prostaglandin synthesis (inhibition of cyclo-oxygenase enzyme). The inhibition of cyclo-oxygenase does not result in an increase formation of leukotriene. As with other non-steroidal anti-inflammatory drugs the mechanism of the analgesic action of Lornoxicam has not been fully determined.

Active ingredient: Lornoxicam.

Reported side effects: Common : Abdominal pain, diarrhea, dyspepsia, nausea, vomiting, dizziness, headache, increase in blood urea nitrogen and creatinine levels, increase in serum transaminase levels and alkaline phosphatase level. Uncommon : Constipation, dysphagia, dry mouth, flatulence, gastritis, gastro- esophageal reflux, peptic ulceration and/or gastrointestinal bleeding, stomatitis, hemorrhoidal bleeding, thrombocytopenia, increased bleeding time, anemia, decrease in erythrocytes, hemoglobin, leucocytes, alopecia, dermatitis, pruritus, increased sweating ,rash urticaria, purpura, ecchymoses, insomnia, somnolence, malaise, weakness, flushing, aseptic meningitis, edema, hypertension, palpitations, tachycardia, hypotension, drowsiness, dizziness, vertigo, paraesthesia, tremor,taste perversion, dyspnoea, bronchospasm, cough, rhinitis, micturation disorder, agitation, depression, liver function abnormalities, myalgia, leg cramps, conjunctivitis, vision disorders, tinnitus, allergic reactions, alteration in appetite and weight changes.

Known drug interactions: Sulphonylureas , Other non-steroidal anti-inflammatory medicines and aspirin , loop diuretics and thiazide diuretics , ACE inhibitors , Lithium , Methotrexate , Cyclosporine , Cimetidine , Digoxin , CYP2C9 isoenzymes such as phenytoin, amiodarone, miconazole, tranylcypromine and rifampicin.

Dosage for the Treatment of Pain : A dose of 8mg to 16mg per day is recommended and should be taken in 2 single doses. The daily dose should not exceed 16mg. Dosage for the Treatment of Rheumatoid Arthritis and Osteoarthritis : The recommended daily dose is 8mg-16mg preferably given as 8mg twice daily. Children : Not recommended . Always consult from your doctor or pharmacist for dose adjustments.

Active ingredient: Lornoxicam. Labelled strength: 8mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Lornex Pharmaceuticals (Pvt) Ltd.. Country of origin: Pakistan.