Cordarone 200mg Tablets 28s

What it is used for: Arrhythmia.

Indications as listed by the manufacturer: Amiodarone can be used to: • Treat uneven heartbeats where other medicines either have not worked or cannot be used • Treat an illness called Wolff-Parkinson-White Syndrome. This is where your heart beats unusually fast • Treat other types of fast or uneven heartbeats known as “atrial flutter” or “atrial fibrillation”. Amiodarone Tablets are used only when other medicines can not be used.

How it works: Amiodarone is a Class III antiarrhythmic agent prolonging the action potential duration and hence refractory period of atrial, nodal and ventricular tissues, thereby giving a very broad spectrum of activity. An increase in the refractory period of the atrial cells is a major contributing action to the control of atrial tachyarrhythmias.

Active ingredient: Amiodarone HCl.

Reported side effects: Dermatologic: Solar dermatitis/photosensitivity. Neurologic: Malaise and fatigue, tremor/abnormal involuntary movements, lack of coordination, abnormal gait/ataxia, dizziness, paresthesias. Gastrointestinal: Constipation, anorexia. Ophthalmologic: Visual disturbances. Hepatic: Abnormal liver-function tests. Respiratory: Pulmonary inflammation or fibrosis .

Known drug interactions: Class I and III antiarrhythmics, lithium, certain phenothiazines, tricyclic antidepressants, certain fluoroquinolone and macrolide antibiotics, IV pentamidine, and azole antifungals , digoxin, beta blockers, verapamil, diltiazem, clonidine , certain protease inhibitors, loratadine, cimetidine, trazodone) , HMG-CoA reductase inhibitors

The standard recommended dose is 5 mg/kg body weight given by intravenous infusion over a period of 20 minutes to 2 hours. This should be administered as a dilute solution in 250 mL 5% glucose. This may be followed by repeat infusions up to a maximum of 1200 mg per day (approximately 15 mg/kg body weight) in up to 500 mL 5% glucose per 24 hours, the rate of infusion being adjusted on the basis of clinical response. OR As directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Amiodarone HCl. Labelled strength: 200MG.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Cordarone Healthcare (Pvt) Ltd.. Country of origin: Pakistan.