Cofcol Elixir 120ml

What it is used for: Fever & Cough.

Indications as listed by the manufacturer: It is used in : Common cold , Influenza , Fever associated with common cold and flu , Muscle ache, Nasal congestion , Sinus congestion , Headache and sinus pain , Sneezing , Itchy and watery eyes .

How it works: Paracetamol works to stop the pain messages from getting through to the brain. It also acts in the brain to reduce fever . Chlorpheniramine: This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose. Pseudoephedrine is a sympathomimetic with a mixed mechanism of action, direct and indirect. It indirectly stimulates alpha-adrenergic receptors, causing the release of endogenous norepinephrine from the granularity of neurons, while it directly stimulates beta-adrenergic receptors. Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other condition.

Active ingredient: Paracetamol , Pseudoephedrine HCl , Chlorpheniramine maleate , Dextromethorphan HBr , Vitamin C.

Reported side effects: Paracetamol : Thrombocytopaenia, Anaphylaxis cutaneous hypersensitivity reactions including amoung others skin rashes, angiodema, stevens johnson syndrome, toxic epidermal necrosis, bronchospasm in patients sensitive to aspirin and other NSAIDs, hepatic dysfuction. Phenylephrine : Nervousness, Headache, Dizziness, Insomnia, Increased blood pressure, Vomiting, nausea, Mydriasis, acute angle closure glaucoma, most likely to occur in those with closed angle glaucoma Tachycardia, Palpitations Allergic reactions (e.g. rash, urticaria, allergic dermatitis) Dysuria, urinary retention. This is most likely to occur in those with bladder outlet obstruction such as prostatic hypertrophy. Chlorphenamine : Allergic reactions, angioedema, anaphylactic reactions Anorexia, Confusion, excitation, irritability, nightmares, Disturbance in attention, abnormal coordination, dizziness, headache Sedation, somnolence Blurred vision, Hypotension, Thickening of bronchial, Secretions, Nausea, dry mouth, Vomiting, abdominal pain, diarrhoea, dyspepsia, Exfoliative dermatitis, rash, urticaria, photosensitivity, Muscle twitching, muscle Weakness, Urinary retention, Fatigue, Chest tightness.

Known drug interactions: The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol-containing products with increased risk of bleeding;occasional doses have no significant effect. Concomitant administration of pseudoephedrine hydrochloride-containing products andMAOIs (or within two weeks of stopping of MAOI) may lead to hypertensive crisis. The anticholinergic effects of chlorpheniramine are intensified by MAOIs. Concomitant use of this medication with sympathomimetic agents (such asdecongestants, appetite suppressants and amphetamine-like psychostimulants) which interfere with the catabolism of sympathomimetic amines, may occasionally cause a rise in blood pressure. Pseudoephedrine-containing products may antagonise the effect of certain classes ofantihypertensives (e.g. beta blockers, methyl-dopa, reserpine, debrisoquine, guanethidine).Concurrent use of chlorphenamine and hypnotics or anxiolytics may potentiatedrowsiness. Concurrent use of alcohol may have a similar effect. Chlorphenamine inhibits phenytoin metabolism and can lead to phenytoin toxicity.

1-3 years: ½ teaspoonful two times a day, 3-6 years: 1 tablespoonful two times a day, 6-12 years or above: 2 tablespoonful two times a day or as directed by your physician.

Active ingredient: Paracetamol , Pseudoephedrine HCl , Chlorpheniramine maleate , Dextromethorphan HBr , Vitamin C.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Cofcol Healthcare (Pvt) Ltd.. Country of origin: Turkey.