Calzem SR 60mg 20 Tablets

What it is used for: Angina.

Indications as listed by the manufacturer: Diltiazem Hydrochloride used to: • Treat (long-term) and prevent angina pectoris • Treat mild to moderate high blood pressure .

How it works: Diltiazem HCl retard belongs to the group of the calcium antagonists. Diltiazem HCl retard is a drug that lowers the heart rate. It has a vasodilating action. As a result, the blood flow of the heart is improved and the pain in the chest due to a shortage of oxygen in the heart muscle avoided. Blood flow in the arteries is also improved and decreases the elevated blood pressure. The effect lasts for 24 hours, therefore one capsule per day is sufficient.

Active ingredient: Diltiazem HCl.

Reported side effects: Very common (may affect more than 1 in 10 people): The accumulation of fluid in ankles, legs or arms (peripheral edema).Common (may affect up to 1 in 10 people): Dizziness, headache , some disorder in the conduction of the heart, leading to arrhythmias (1st, 2nd or 3rd degree , heart block or bundle branch block), palpitations (palpitations) , flushing (sudden reddening of the face and neck, flush) , indigestion with fullness or pain in the stomach, belching, nausea, vomiting and heartburn (dyspepsia), stomach pain, constipation. , redness of the skin (erythema) , feeling unwell (malaise) , fatigue. Uncommon (may affect up to 1 in 100 people): Nervousness, sleeplessness (insomnia) , slow heart rate (bradycardia) , drop in blood pressure caused by a rapid rise from a sitting or lying position that sometimes in dizziness (orthostatic hypotension) , vomiting, diarrhea , increase in liver enzymes.

Known drug interactions: Lithium , nitrate derivatives, alpha-blockers, amiodarone, digoxin, beta blockers, antiarrhythmics , theophylline , carbamazepine , cyclosporine , benzodiazepines such as midazolam and triazolam , methylprednisolone , statins , rifampicin , cimetidine and ranitidine .

Adults : The maintenance dose is one tablet (60mg) three times a day. Up to 8 tablets (480mg) a day may be used. Your doctor will decide on the best dose for you. Elderly and those with liver or kidney problems : Initially one tablet (60mg) twice a day. Your doctor may adjust the dose according to your response. Use in children : Not recommended OR As directed by your physician.

Active ingredient: Diltiazem HCl. Labelled strength: 60mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Calzem Laboratories (Pvt) Ltd.. Country of origin: Pakistan.