Artinil K 75mg 2x10 Tablets

What it is used for: Pain Relief.

Indications as listed by the manufacturer: It is used to treat pain and inflammation.

How it works: Diclofenac has analgesic, anti-inflammatory, and antipyretic properties. The mechanism of action of diclofenac , like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2).Diclofenac is a potent inhibitor of prostaglandin synthesis in vitro. Diclofenac concentrations reached during therapy have produced in vivo effects. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal models. Prostaglandins are mediators of inflammation. Because diclofenac is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.

Active ingredient: Diclofenac potassium.

Reported side effects: These uncommon side effects may affect between 1 and 10 in every 1000 patients, especially when taking a high daily dose (150 mg) for a long period of time : Sudden and oppressive chest pain (signs of myocardial infarction or heart attack) , Breathlessness, difficulty of breathing when lying down, swelling of the feet or legs (signs of cardiac failure).These rare or very rare side effects may affect from less than 1 to 10 in every 10,000 patients : Spontaneous bleeding or bruising (signs of thrombocytopenia) , High fever, frequent infections, persistent sore throat (signs of agranulocytosis) , Difficulty of breathing or swallowing, rash, itching, hives, dizziness (signs of hypersensitivity, anaphylactic and anaphylactoid reactions) , Swelling mainly of the face and throat (signs of angioedema ) , Disturbing thoughts or moods (signs of psychotic disorders) , Impaired memory (signs of memory impairment) , Seizures (signs of convulsions) , Anxiety , Stiff neck, fever, nausea, vomiting, headache (signs of aseptic meningitis). These side effects may affect between 1 and 10 in every 100 patients : Headache, dizziness, vertigo, nausea, vomiting, diarrhea, indigestion (signs of dyspepsia), abdominal pain, flatulence, loss of appetite (signs of decreased appetite), abnormal liver function test results (e.g. level of transaminases increased), skin rash, skin reaction such as redness or swelling at the site of injection.

Known drug interactions: Lithium or selective serotonin-reuptake inhibitors (SSRIs) , Digoxin , Diuretics , ACE inhibitors or beta-blockers , acetylsalicylic acid or ibuprofen , Corticosteroids , Blood thinners ,Medicines used to treat diabetes, except insulin , Methotrexate , Ciclosporin, Tacrolimus , Trimethoprim , Quinolone antibacterials , Voriconazole , Phenytoin.

Adults : Pain - 50mg every 8hr or 100mg 1st dose,then 50mg every 8hr. Max: 150mg/day (200mg/day on 1st day). Osteoarthritis : 50mg every 8 hour or every 6 hr. Max:225mg/day. Dysmenorrhoea: 50mg every 8 hr or 100mg 1st dose, then 50mg every 8hr. Max: 150mg/day (200mg/day on 1st day). Children : Rheumatic disease and musculoskeletal disorders : 14-18yr, 75-100mg daily in 2-3 divided doses. Fever in ear, nose or throat infection : 9-18yr and body weight over 35kg, upto 2mg/kg (max 100mg) daily in divided doses. Always consult ypur doctor or pharmacist for dose adjustments.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Diclofenac potassium. Labelled strength: 75mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Artinil Laboratories (Pvt) Ltd.. Country of origin: United Arab Emirates.