Artho plus Tablets 75mg 20s

What it is used for: Osteoarthritis.

Indications as listed by the manufacturer: It is indicated for treatment of the signs and symptoms of osteoarthritis or rheumatoid arthritis in patients at high risk of developing NSAID-induced gastric and duodenal ulcers and their complications.

How it works: Diclofenac Sodium/Misoprostol is a nonsteroidal anti-inflammatory drug (NSAID). In pharmacologic studies, diclofenac sodium has shown anti-inflammatory, analgesic and antipyretic properties. The mechanism of action of diclofenac sodium, like other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition.

Active ingredient: Diclofenac sodium + Misoprostol.

Reported side effects: Inflammation, bleeding, ulceration, and perforation of the stomach, small intestine, or large intestine , thrombotic events, myocardial infarction, and stroke , ulcer or gastrointestinal bleeding .

Known drug interactions: ACE-Inhibitors , Aspirin , Digoxin , Warfarin , Methotrexate , Cyclosporine , Lithium , Antacids , Diuretics

Osteoarthritis: The recommended dosage for maximal GI mucosal protection is 50mg/200mcg tid. For patients who experience intolerance, 75mg/200mcg bid or 50mg/200mcg bid can be used, but are less effective in preventing ulcers. This fixed combination product, is not appropriate for patients who would not receive the appropriate dose of both ingredients. Children : Not recommended . OR As directed by your physician .

Active ingredient: Diclofenac sodium + Misoprostol. Labelled strength: 75mg/200mcg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Artho Laboratories (Pvt) Ltd.. Country of origin: Pakistan.