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Hope Pharmacy
Abbott

Apixaget 25mg Tab 30s

A tablet containing Apixaban, indicated for Stroke.

Rs. 390

100ml Syrup

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Quantity
Apixaget 25mg Tab 30s quantity: 1
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Total for 1 pack: Rs. 390

What it is used for: Stroke.

Indications as listed by the manufacturer: Apixaban is indicated for: • The prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective knee or hip replacement surgery. • The prevention of stroke and systemic embolism in patients with atrial fibrillation. • The treatment of venous thromboembolic events (deep vein thrombosis [DVT], pulmonary embolism [PE]) and prevention of recurrent DVT and PE.

How it works: Apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound factor Xa and prothrombinase activity. Apixaban has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting factor Xa, Apixaban prevents thrombin generation and thrombus development.

Active ingredient: Apixaban.

Reported side effects: Common: Haemorrhage, haematoma, epistaxis, gastrointestinal haemorrhage, rectal haemorrhage, gingival bleeding, haematuria and contusion. Uncommon: Pruritus, eye haemorrhage (including conjunctival haemorrhage), haemoptysis, haematochezia, abnormal vaginal haemorrhage, urogenital haemorrhage, occult blood positive, traumatic haemorrhage, post procedural haemorrhage and incision site haemorrhage. Rare: Brain haemorrhage and respiratory tract haemorrhage .

Known drug interactions: Inhibitors of CYP3A4 and P-gp , g. Inducers of CYP3A4 and P-gp (e.g., rifampin, carbamazepine, phenytoin, St. John’s wort) , thrombolytic agents, fibrinolytics, GPIIb/IIIa receptor antagonists, thienopyridines (e.g., clopidogrel), dipyridamole, dextran, heparin, aspirin, chronic NSAID and sulfinpyrazone.

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Bundle total

Rs. 3,420Rs. 3,685

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Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.