Acogest 100mg Tab 20s

What it is used for: Dyspepsia.

Indications as listed by the manufacturer: Acotiamide HCl Hydrate is indicated for the treatment of postprandial bloating, epigastric distention, and early satiety in functional dyspepsia.

How it works: Acotiamide inhibits acetylcholinesterase (AChE) activity by a mixed type of inhibition comprising competitive inhibition and noncompetitive inhibition. AChE inhibition by Acotiamide suppresses the degradation of acetylcholine (ACh) released from cholinergic nerve terminals, which results in enhancement of ACh-induced contraction and motility of the gastric antrum and gastric body, thereby increasing postprandial antral motility and improving antral hypomotility and delayed gastric emptying.

Active ingredient: Acotiamide.

Reported side effects: Rash, urticaria, increased white blood cell count, dizziness, diarrhea, constipation, nausea, vomiting, stomach ache, stomatitis, ALT increase, AST increase, gamma-GTP increase, increased blood bilirubin, increased blood ALP, increased prolactin in the blood and increased triglycerides in the blood.

Known drug interactions: Drugs with anticholinergic effect : Atropine Sulfate Hydrate, Butylscopolamine, Bromide, etc, there is a possibility that the action of the drug may be attenuated. Since Acotiamide has an acetylcholinesterase inhibitory effect, the action of this drug is suppressed by concomitant use of anticholinergic agents. Choline activators and cholinesterase inhibitors : Drugs like Acetylcholine Chloride, Neostigmine, Bromide alone or in combination may enhance the effect or has an acetylcholine receptor stimulating effect .

The usual adult dosage is 100mg of Acotiamide HCl Hydrate administered orally three times daily before a meal.

Active ingredient: Acotiamide. Labelled strength: 100mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Acogest Healthcare (Pvt) Ltd.. Country of origin: Pakistan.