Xatral SR Tablets 5mg 2x14s

What it is used for: Benign Prostatic Hyperplasia.

Indications as listed by the manufacturer: It is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH) ; it is indicated as adjunctive therapy with urethral catheterization for Acute Urinary Retention related to BPH and management following catheter removal.

How it works: The symptoms associated with benign prostatic hyperplasia (BPH) such as urinary frequency, nocturia, weak stream, hesitancy and incomplete emptying are related to two components, anatomical (static) and functional (dynamic). The static component is related to the prostate size. Prostate size alone does not correlate with symptom severity. The dynamic component is a function of the smooth muscle tone in the prostate and its capsule, the bladder neck, and the bladder base as well as the prostatic urethra. The smooth muscle tone is regulated by alphaadrenergic receptors. Alfuzosin exhibits selectivity for alpha1-adrenergic receptors in the lower urinary tract. Blockade of these adrenoreceptors can cause smooth muscle in the bladder neck and prostate to relax, resulting in an improvement in urine flow and a reduction in symptoms of BPH. Alfuzosin HCl extended-release is a selective antagonist of post-synaptic alpha1-adrenoreceptors, which are located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.

Active ingredient: Alfuzosin.

Reported side effects: Feeling dizzy or faint , Headache , Feeling sick (nausea) , Stomach pain , Feeling dizzy, lightheaded, or faint when you stand or sit up quickly (postural hypotension) , Fast Heart beat (tachycardia) and palpitations (pounding in the chest and uneven heartbeat) , Chest Pain , Drowsiness , Diarrhoea , Dry mouth , Rash and itching , Flushes , Water retention (may cause swollen arms or legs). ? Runny nose, itching, sneezing, and stuffy nose , General feeling of being unwell , Problems with your vision.

Known drug interactions: Doxazosin, indoramin, prazosin, terazosin, tamsulosin, or phenoxybenzamine , You are taking medicines for chest pain (angina) , itraconazole , ritonavir , clarithromycin, telithromycin , nefazodone .

Adults : 10 mg once daily or 2.5mg 3 times daily . Elderly : 5 mg morning and evening . Children : Not recommended . First dose may cause collapse due to hypotensive effect ( therefore should be taken on retiring to bed ) . Patients should be warned to lie down if symptoms such as dizziness fatigue or sweating develop and to remain lying down until they abate completely . OR As directed by your physician.

Active ingredient: Alfuzosin. Labelled strength: 5mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Xatral Pharmaceuticals (Pvt) Ltd.. Country of origin: Pakistan.