Avodart Capsules 0/5mg 30s

What it is used for: Benign Prostatic Hyperplasia.

Indications as listed by the manufacturer: It is used to treat men with an enlarged prostate (benign prostatic hyperplasia) ; A non-cancerous growth of the prostate gland , caused by producing too much of a hormone called dihydrotestosterone.

How it works: Dutasteride inhibits the conversion of testosterone to 5a-dihydrotestosterone (DHT). DHT is the androgen primarily responsible for the initial development and subsequent enlargement of the prostate gland. Testosterone is converted to DHT by the enzyme 5a-reductase, which exists as 2 isoforms, type 1 and type 2. The type 2 isoenzyme is primarily active in the reproductive tissues, while the type 1 isoenzyme is also responsible for testosterone conversion in the skin and liver. Dutasteride is a competitive and specific inhibitor of both type 1 and type 2 5a-reductase isoenzymes, with which it forms a stable enzyme complex. Dissociation from this complex has been evaluated under in vitro and in vivo conditions and is extremely slow. Dutasteride does not bind to the human androgen receptor.

Active ingredient: Dutasteride.

Reported side effects: Skin rash (which can be itchy) • Hives (like a nettle rash) • Swelling of the eyelids, face, lips, arms or legs • Not able to achieve or maintain an erection (impotence), this may continue after you stop taking Dutasteride • decreased sex drive (libido), this may continue after you stop taking Dutasteride • Difficulty with ejaculation, such as a decrease in the amount of semen released during sex, this may continue after you stop taking Dutasteride • Breast enlargement or tenderness (gynecomastia) • Dizziness when taken with tamsulosin • heart failure (heart becomes less efficient at pumping blood around the body • Hair loss (usually from the body) or hair growth.

Known drug interactions: Verapamil or Diltiazem • ritonavir or indinavir (for HIV) • Itraconazole or ketoconazole • Nefazodone (an antidepressant) • Alpha-blockers (for enlarged prostate or high blood pressure).

Adults : Males ( including elderly ) : The recommended dose is 1 capsule (0.5 mg) taken orally once a day . Children : Not recommended . Or As directed by your physician.

Active ingredient: Dutasteride. Labelled strength: 0.5mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Avodart Laboratories (Pvt) Ltd.. Country of origin: Switzerland.