Paraxyl Tablets 25mg CR 30s

What it is used for: Depression.

Indications as listed by the manufacturer: It is indicated for the symptomatic relief of Major Depressive Disorder.

How it works: The efficacy of paroxetine in the treatment of major depressive disorder, social anxiety disorder, obsessive compulsive disorder (OCD), panic disorder (PD), generalized anxiety disorder (GAD), and posttraumatic stress disorder (PTSD) is presumed to be linked to potentiation of serotonergic activity in the central nervous system resulting from inhibition of neuronal reuptake of serotonin (5-hydroxy-tryptamine, 5-HT).

Active ingredient: Paroxetine HCl.

Reported side effects: Abnormal bleeding, predominantly of the skin and mucous membranes (mostly ecchymosis), thrombocytopenia , allergic reactions (including urticaria and angioedema , syndrome of inappropriate anti-diuretic hormone secretion (SIADH) , hyponatraemia , somnolence, insomnia, agitation, abnormal dreams (including nightmares) , confusion, hallucinations , dizziness, tremor, headache.

Known drug interactions: L-tryptophan, triptans, tramadol, SSRIs, lithium, fentanyl and St. John’s Wort – Hypericum perforatum – preparations , Pimozide , carbamazepine, rifampicin, phenobarbital, phenytoin , Fosamprenavir , ritonavir , Procyclidine , carbamazepine, phenytoin, sodium valproate , tricyclic antidepressants, phenothiazine neuroleptics, risperidone, atomoxetine, certain Type 1c antiarrhythmics and metoprolol.

Depression - Adult dose : Initially 20mg once daily in the morning with food. If necessary increase gradually after minimum 2 week in 10mg increments , max 50mg daily. Obsessive compulsive disorder : Adults : Initially 20 mg once daily in the morning with food . Increase wkly 10 mg increments to 40 mg daily ; max 60 mg daily. Panic disorders : Adults : Initially 10 mg once daily in the morning with food . Increase wkly in 10 mg increments to 40 mg daily ; max 50 mg daily. Generalized anxiety disorder : Adults : Initially 20mg once daily , preferably in the morning ( if dose is increased , adjust in steps of 10mg/day at 1 wk intervals ) . Children : Not recommended . OR As directed by your physician.

Active ingredient: Paroxetine HCl. Labelled strength: 25mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Paraxyl Pharma (Pvt) Ltd.. Country of origin: Pakistan.