Duricef Capsules 500mg 12s

What it is used for: Bacterial Infection.

Indications as listed by the manufacturer: Cefadroxil is indicated in the treatment of mild to moderate infections of the respiratory tract (Pharyngitis & tonsillitis), urinary tract, skin and skin structures and bone caused by susceptible organisms and as an alternative to penicillin in patients with a history of hypersensitivity reactions.

How it works: Cefadroxil is a first-generation cephalosporin antibiotic. It is bactericidal, and acts by inhibiting synthesis of the bacterial cell wall. Bacterial cell wall is held rigid and protected against osmotic rupture by peptidoglycan. Cefadroxil inhibits the final cross linking stage of peptidoglycan production by binding to and inactivating transpeptidase, which is a penicillin binding protein on the inner surface of the bacterial cell membrane may result in overgrowth of non-susceptible organisms. Careful observation of the patients is essential. If super infection occurs during the therapy, appropriate measures should be taken.

Active ingredient: Cefadroxil.

Reported side effects: It is generally well-tolerated. The common side effects are gastrointestinal disturbances (diarrhoea), hypersensitivity reactions (skin rashes). Other side effects are nausea and vomiting. Other reactions reported rarely are genital pruritus, genital moniliasis, vaginitis. Sometimes it causes anaphylaxis, erythema multiforme, toxic epidermal necrolysis, fever, abdominal pain, super infection, renal dysfunction, toxic nephropathy, hepatic dysfunction including cholestasis, aplastic anemia, hemolytic anemia, and hemorrhage. Several cephalosporins have been implicated triggering seizures, particularly in patients with renal impairment .

Known drug interactions: Loop diuretics , anticoagulants , other antibiotics , antiplatelets , colestyramine.

Adults : 500mg-1gm twice daily or 1gm once daily or 2gm daily in two divided doses. Children : Under 1yr, 25mg/kg daily in divided doses ; 1-6yr, 250mg twice daily; over 6yr, 500mg twice daily. Upper Respiratory infection : Adults : 1gm once daily or 500mg twice daily for 10days. Children : 15mg/kg every 12hr or 30mg/kg daily. Urinary Tract Infections : Adults : Uncomplicated lower UTI : 1-2gm/day given once daily or in two divided doses. Other UTIs : 1gm twice daily. Children : 15mg/kg every 12hr. Skin Infection : Adults : 1gm once daily or 500mf twice daily . Children : 15mg/kg every 12hr ( or 30mg/kg once daily for impetigo) OR As directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Cefadroxil. Labelled strength: 500mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Duricef Pharma (Pvt) Ltd.. Country of origin: Pakistan.