Erythrocin 250mg Tab

What it is used for: Bacterial Infection.

Indications as listed by the manufacturer: It is used to prevent and treat infections such as: • Throat and sinus infections • Chest infections, such as bronchitis and pneumonia • Ear infections • Mouth and dental infections • Eye infections • Skin and tissue infections, such as acne • Stomach and intestinal infections .

How it works: Erythromycin exerts its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections: Gram positive bacteria - Listeria monocytogenes, Corynebacterium diphtheriae (as an adjunct to antitoxin), Staphylococci spp, Streptococci spp (including Enterococci). Gram negative bacteria - Haemophilus influenzae, Neisseria meningitidis, Neisseria gonorrhoeae, Legionella pneumophila, Moraxella (Branhamella) catarrhalis, Bordetella pertussis, Campylobacter spp. Mycoplasma - Mycoplasma pneumoniae, Ureaplasma urealyticum. Other organisms - Treponema pallidum, Chlamydia spp, Clostridia spp, L-forms, the agents causing trachoma and lymphogranuloma venereum

Active ingredient: Erythromycin stearate.

Reported side effects: GI upset , Cholestatic jaundice , allergic reactions , reversible hearing loss , pancreatitis , cardiac effects , Myssthaenia like syndrome , Stevens-Johnson syndrome , toxic epidermal necrolysis , hepatotoxicity , hypotension , interstitial nephritis , hallucinations , chest pain , fever , malaise , QT Prolongation.

Known drug interactions: Astemizole, terfenadine or mizolastine , domperidone pimozide ergotamine or dihydroergotamine cisapride , statins protease inhibitors , oral contraceptives. , colchicine , cimetidine and omeprazole , clarithromycin, rifabutin, or rifampicin , fluconazole, ketoconazole and itraconazole , digoxin, quinidine or disopyramide , cilostazol , hexobarbitone, phenobarbital or midazolam , Anticoagulants e.g. warfarin, acenocoumarol and rivaroxaban, valproate, carbamazepine or phenytoin, theophylline ciclosporin or tacrolimus , bromocriptine zopiclone or triazolam/alprazolam , alfentanil (a medicine used to provide pain relief) , methylprednisolone , St John’s Wort (a herbal medicine used to treat depression) , verapamil (used to treat high blood pressure and chest pain) , vinblastine .

Adults : 250mg-500mg every 6hr or 500mg-1gm every 12 hr taken before or with meals , up to 4gm daily in divided doses in severe infections. Children : Neonates - 12..5mg/kg every 6hr , 1 month-2yr, 125mg every 6 hr , 2-8yr , 250mg every 6hr. The dose doubled for severe infection. Lower Respiratory Infection : Adults : Usual 250mg every 6 hr or 500mg every 12hr. Children : Usual 30-50mg/kg/day in divided doses . Max : 4gm/day . Upper Respiratory Infection : Adults : Usual : 250mg every 6 hr or 500mg every 12 hr . Children : Usual : 30-50mg/kg/day in divided doses. Max : 4gm/day. OR As directed by your physician.

Active ingredient: Erythromycin stearate. Labelled strength: 250mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Erythrocin Pharma (Pvt) Ltd.. Country of origin: India.