Topagen 25mg 60 Tablets

What it is used for: Seizures.

Indications as listed by the manufacturer: Topiramate belongs to a group of medicines called anti-epileptic medicines. Alone to treat seizures in adults and children over age 6 , with other medicines to treat seizures in adults and children aged 2 years and above - to prevent migraine headaches in adults .

How it works: Topiramate works by reducing the spread of seizure activity in the brain and restoring the normal balance of nerve activity. For epilepsy - brain cells normally talk to each other using electrical signals and chemicals. Seizures can happen when the brain cells are not working properly or working faster than normal.

Active ingredient: Topiramate.

Reported side effects: Common (may affect up to 1 in 10 people) - Seizures (fits) , Anxiety, irritability, changes in mood, confusion, disorientation , Problems with concentration, slowness of thinking, loss of memory, problems with memory (new onset, sudden change or increased severity) , Kidney stone, frequent or painful urination. Uncommon (may affect up to 1 in 100 people) : Increased acid level in the blood (may cause troubled breathing including shortness of breath, loss of appetite, nausea, vomiting, excessive tiredness, and fast or uneven heart beats) , Decreased or loss of sweating (particularly in young children who are exposed to high temperatures) , Having thoughts of serious self-harm, trying to cause serious self-harm , Loss of part of the field of vision. Rare (may affect up to 1 in 1,000 people) : Glaucoma – blockage of fluid in eye causing increased pressure in the eye, pain, or decreased vision , Difficulty thinking, remembering information, or solving problems, being less alert or aware, feeling , sleepy with low energy – these symptoms may be a sign of a high level of ammonia in the blood (hyperammonemia), which can lead to a change in brain function (hyperammonemic encephalop

Known drug interactions: Muscle relaxants and sedatives , risperidone, lithium, hydrochlorothiazide, metformin, pioglitazone, glibenclamide, amitriptyline, propranolol, diltiazem, venlafaxine, flunarazine, St. John's wort (Hypericum perforatum) (a herbal preparation used to treat depression), warfarin used to thin the blood.

Seizures : Adults - Initially 25 mg once daily at night for week , increased in steps of 25-50mg in 2 divided doses every 1-2weeks , usual dose 100-200mg daily in 2 divided doses , adjusted according to response , 1gm daily dose have been in refractory epilepsy , max 500mg daily or as directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Topiramate. Labelled strength: 25mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Topagen Laboratories (Pvt) Ltd.. Country of origin: India.