Tigasor 25mg Capsules 30s

What it is used for: Psoriasis.

Indications as listed by the manufacturer: It is used to treat severe skin problems where the skin has become thick and may be scaly. These skin problems include psoriasis, ichthyosis and keratosis follicularis (Darier’s disease) .

How it works: Acitretin, the active ingredient of Acitretin, is a synthetic aromatic analogue of retinoic acid and the main metabolite of etretinate, which has been used with success for a number of years in the treatment of psoriasis and other disorders of keratinisation. Clinical studies have confirmed that, in psoriasis and dyskeratosis, acitretin brings about a normalisation of epidermal cell proliferation, differentiation and keratinisation in doses at which the side effects are generally tolerable. The effect of Acitretin is purely symptomatic: the mechanism of action is still largely unknown.

Active ingredient: Acitretin.

Reported side effects: Dry, irritated or swollen eyes, which may lead to intolerance of contact lenses ; dry, irritated or runny nose, nose bleeding ; dry mouth, thirst ; dryness or inflammation of the lips, which may be alleviated by application of a fatty ointment. Itching, hair loss, peeling of the skin from the palms of hands or the soles of the feet or even rest of the body ; thinning of the skin ; changes in how the liver is working (shown by blood test); increased levels of fats in your blood (shown by blood test) ; headache; inflammation of the mucous tissue of the mouth, abdominal pain, diarrhoea, feeling sick, being sick; fragile skin, sticky feeling on the skin or a rash, skin inflammation, changes to the texture of the hair, brittle nails, skin infection around a nail, redness of the skin; joint pain, muscle pain; swelling of hands, ankles and feet

Known drug interactions: Methotrexate , Vitamin A and other retinoids (such as isotretinoin and tazarotene) .

Adults : Initially 25-30mg daily for 2 to 4 wk. Titrate against response upto max 75mg daily. Maintenance : 25-50mg daily . Max treatment 6mnth. Children : Not recommended . Or As directed by your physician.

Active ingredient: Acitretin. Labelled strength: 25mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Tigasor Pharma (Pvt) Ltd.. Country of origin: India.