Tegral Tablets 200mg 5x10s

What it is used for: Epilepsy.

Indications as listed by the manufacturer: It is used to treat : • To treat some forms of epilepsy • To treat a painful condition of the face called trigeminal neuralgia • To help control serious mood disorders when some other medicines don’t work .

How it works: Carbamazepine is a sodium channel blocker. It binds preferentially to voltage-gated sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.

Active ingredient: Carbamazepine.

Reported side effects: Up to 1 in 10 people have experienced: Changes in the blood including an increased tendency to bruise or bleed; fluid retention and swelling; weight increase; low sodium in the blood which might result in confusion; headache; double or blurred vision; dry mouth. Up to 1 in 100 people have reported: Abnormal involuntary movements including tremor or tics; abnormal eye movements; diarrhoea; constipation. Up to 1 in 1,000 people have reported: Disease of the lymph glands; folic acid deficiency; a generalised allergic reaction including rash, joint pain, fever, problems with the kidneys and other organs; hallucinations; depression; loss of appetite; restlessness; aggression; agitation; confusion; speech disorders; numbness or tingling in the hands and feet; muscle weakness; high blood pressure (which may make you feel dizzy, with a flushed face, headache, fatigue and nervousness); low blood pressure (the symptoms of which are feeling faint, light headed, dizzy, confused, having blurred vision); changes to heart beat; stomach pain; liver problems including jaundice; symptoms of lupus.

Known drug interactions: Hormone contraceptives , Hormone Replacement Therapy (HRT) , Any medicines for depression or anxiety. , Corticosteroids (‘steroids’) , Anticoagulants , ciprofloxacillin , Antifungals to treat fungal infections , Painkillers containing paracetamol, dextropropoxyphene, tramadol, methadone or buprenorphine ,Other medicines to treat epilepsy , Medicines for high blood pressure or heart problems , Antihistamines (medicines to treat allergy such as hayfever, itch, etc) , Diuretics (water tablets) , Cimetidine or omeprazole (medicines to treat gastric ulcers) , Isotretinoin (a medicine for the treatment of acne) , Metoclopramide or aprepitant (anti-sickness medications) , Acetazolamide (a medicine to treat glaucoma - increased pressure in the eye) , Danazol or gestrinone (treatments for endometriosis) , Theophylline or aminophylline (used in the treatment of asthma) , Ciclosporin, tacrolimus or sirolimus (immunosuppressants used after transplant operations, but also sometimes in the treatment of arthritis or psoriasis) , Drugs to treat schizophrenia (e.g. paliperidone, aripiprazole) , Cancer drugs (e.g. temsirolimus, cyclophasphamide, lapatinib) , The anti-malarial drug, mefloquine , Drugs to treat HIV , Levothyroxine (used to treat hypothyroidism) , Tadalafil (used to treat impotence) , Albendazole (used to treat worms) , Bupropion (used to help stop smoking) , A herbal remedy called St John’s Wort or Hypericum , Drugs or supplements containing Vitamin B (nicot

Adults : Epilepsy : Initially 100-200mg once or twice daily increasing slowly to optimum dosage, usually 800mg-1.2gm daily in divided doses. Max 1.5gm daily. Manic depressive psychosis : Initially 400mg daily in divided doses increasing gradually until symptoms controlled ; max 1.6gm individed doses. Usual range , 400-600mg daily. Always consult your doctor or pharmacist for dose adjustments.

Active ingredient: Carbamazepine. Labelled strength: 200mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Tegral Laboratories (Pvt) Ltd.. Country of origin: India.