Daplazole 60mg Cap 30s

What it is used for: Gastroesophageal Reflux Disease.

Indications as listed by the manufacturer: Dexlansoprazole is indicated in patients 12 years of age and older: • For healing of all grades of erosive esophagitis (EE) for up to eight weeks. • To maintain healing of EE and relief of heartburn for up to six months. • For the treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD) for four weeks.

How it works: Dexlansoprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the (H+, K+)-ATPase at the secretory surface of the gastric parietal cell. Dexlansoprazole has been characterized as a gastric proton-pump inhibitor, in that it blocks the final step of acid production.

Active ingredient: Dexlansoprazole.

Reported side effects: Common : Diarrhea, abdominal pain, nausea, upper respiratory tract infection, vomiting and flatulence. Less Common : Anemia, lymphadenopathy, angina, arrhythmia, bradycardia, chest pain, edema, myocardial infarction, palpitation, tachycardia, ear pain, tinnitus, vertigo, goiter, eye irritation, eye swelling, abdominal discomfort, abdominal tenderness, abnormal feces, anal discomfort, Barrett’s esophagus, bezoar, abnormal bowel sounds, breath odor, colitis microscopic, colonic polyp, constipation, dry mouth, duodenitis, dyspepsia, dysphagia, enteritis, eructation, esophagitis, gastric polyp, gastritis, gastroenteritis, gastrointestinal disorders.

Known drug interactions: Rilpivirine, atazanavir and nelfinavir , Saquinavir , Warfarin , Methotrexate , Digoxin , iron salts, erlotinib, dasatinib, nilotinib, mycophenoloate mofetil, ketoconazole/itraconazole , Tacrolimus , tetrahydrocannabinol (THC) , CYP2C19 or CYP3A4 Inducers (St. John’s Wort, rifampin) , CYP2C19 or CYP3A4 Inhibitors (Voriconazole)

Adults : Healing of Erosive oesophagitis (EE) : Short term treatment : One 60mg capsule once daily for up to 8 weeks . Maintenance of Healed EE and Relief of Heartburn : One 30mg capsule once daily . Symptomatic Non-Erosive GERD : One 30mg capsule daily for 4 weeks . Children : Not recommended . Always consult your doctor or pharmacist for dose adjustment.

Active ingredient: Dexlansoprazole. Labelled strength: 60mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Daplazole Laboratories (Pvt) Ltd.. Country of origin: Pakistan.