Baclin 10mg Tablets 30s

What it is used for: Muscle Relaxant.

Indications as listed by the manufacturer: It is used to reduce and relieve the excessive tension in your muscles (spasms) occurring in various illnesses such as cerebral palsy, multiple sclerosis, cerebrovascular accidents, spinal cord diseases and other nervous system disorders.

How it works: Baclofen is an antispastic agent acting at the spinal level. A gamma-aminobutyric acid (GABA) derivative, chemically unrelated to other antispastic agents. Baclofen depresses monosynaptic and polysynaptic reflex transmission, probably by stimulating the GABAB-receptors. This stimulation in turn inhibits the release of the excitatory amino acids glutamate and aspartate. Neuromuscular transmission is unaffected by baclofen. The major benefits of baclofen stem from its ability to reduce painful flexor spasms and spontaneous clonus thereby facilitating the mobility of the patient, increasing their independence and helping rehabilitation. Baclofen also exerts an antinociceptive effect. General well being is often improved and sedation is less often a problem than with centrally acting drugs. Baclofen stimulates gastric acid secretion .

Active ingredient: Baclofen.

Reported side effects: Drowsiness • sleepiness • feeling sick • dry mouth • headache, dizziness or light-headedness • fatigue • excessively weak limbs or feeling tired and exhausted, aching muscles • unsteadiness, trembling or other problems with muscle control • confusion, depression • mood changes with extreme excitement, • hallucinations (seeing or feeling or hearing things that are not really there) or nightmares, • low blood pressure (fainting) • stomach upset including retching, vomiting, diarrhoea or constipation • sleeplessness • skin rash, excessive sweating .

Known drug interactions: Other medicines to relax muscles e.g. tizanidine • Medicines to treat mood disorders such as lithium or tricyclic depressants such as amitriptyline • Medicines for high blood pressure e.g. diltiazem • Medicines which affect the kidney, e.g. ibuprofen • Medicines for Parkinson’s disease e.g. levodopa and carbidopa • Medicines which slow down the nervous system, such as anti-histamines (e.g. promethazine), sedatives (e.g. temazepam), opiates for pain relief (e.g. morphine, fentanyl) and anti-epileptic medicines (e.g. carbamazepine).

Adults : The recommended dose is 5 mg Baclofen (half a tablet) 3 times a day for 3 days, then - 10 mg Baclofen (1 tablet) 3 times a day for the next 3 days, then - 15 mg Baclofen (one and half tablets) 3 times a day for 3 days, then - 20 mg Baclofen (2 tablets) 3 times a day for the next 3 days. The maximum daily dose is 100 mg except if you are in hospital when a higher dose may be used. Children: Children's treatment usually starts with a very low dose (approximately 0.3 mg/kg/day), in 2-4 divided doses (preferably in 4 doses). The dosage is then gradually increased until it becomes sufficient for the child's individual requirements, this may be between 0.75 and 2 mg/kg body weight. The total daily dose should not exceed a maximum of 40 mg/day in children below 8 years of age. In children over 8 years of age a maximum daily dose of 60 mg/day may be given . OR As directed by your physicians.

Active ingredient: Baclofen. Labelled strength: 10mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Baclin Healthcare (Pvt) Ltd.. Country of origin: United Kingdom.