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Hifolic 400mcg Tablets 30s

A tablet containing Quatrefolic, indicated for Folic Acid Supplements.

Rs. 1,800Rs. 1,955-8%

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20 Tablets

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Hifolic 400mcg Tablets 30s quantity: 1
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Total for 1 pack: Rs. 1,800

What it is used for: Folic Acid Supplements.

Indications as listed by the manufacturer: During pregnancy and lactation • Pregnant women for prevention of neural tube defect in babies • As a dietary supplement in adults and older people • To prevent risk of spontaneous abortions • In hyperhomocysteinemia • Folate deficiency caused by some medicines (e.g. those used to treat epilepsy such as phenytoin, phenobarbital and primidone) • Folate deficiency caused by long-term red blood cell damage or kidney dialysis • In Depression, Cognitive impairment, Dementia and Alzheimer's disease .

How it works: The mechanism of action of Quatrefolic is related to the action of 5-methyltetrahydrofolate, the active part of the proprietary ingredient. 5-methyltetrahydrofolate derives from tetrahydrofolic acid, through a series of metabolic reactions. Tetrahydrofolic acid acts as a coenzyme in several vital metabolic reactions participating in the transfer as acceptors and donors of various one-carbon fragments, involved in the biosynthesis of nucleotides purines and pyrimidines and in the metabolism of several important amino acids. In concern with vitamin B12, folate coenzymes allow the conversion of the amino acid homocysteine to methionine, the lack of this conversion has been associated with various pathologies and diseases. Conversion of tetrahydrofolic acid to 5-methyltetrahydrofolate is mediated by the action of the enzyme methylenetetrahydrofolate reductase. Supplementation with 5-methyltetrahydrofolate might be preferable to folic acid, being it is immediately available to react with homocysteine to avoid the possibility of hyperhomocysteinaemia.

Active ingredient: Quatrefolic.

Reported side effects: Gastrointestinal disorders : Anorexia, nausea, abdominal distension and flatulence ; Immune system disorders : Allergic reactions, comprising erythema, rash, pruritus, urticaria, dyspnea, and anaphylactic reactions (including shock) .

Known drug interactions: Fosphenytoin : Folic acid along with fosphenytoin might decrease the effectiveness of fosphenytoin for preventing seizures ; Methotrexate : Folic acid along with methotrexate might decrease the effectiveness of methotrexate ; Phenobarbital : Folic acid can decrease the phenobarbital effect for preventing seizures ; Phenytoin : Folic acid along with phenytoin might decrease the effectiveness of phenytoin and increase the possibility of seizures ; Primidone : Folic acid along with primidone might decrease how well primidone works for preventing seizures ; Pyrimethamine : Folic acid might decrease the effectiveness of pyrimethamine for treating parasite infections ; Sulfasalazine : Sulfasalazine can reduce the absorption of folic acid.

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Rs. 10,555Rs. 11,705

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Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.