Diamicron MR Tablets 60mg 2x10s

What it is used for: Diabetes.

Indications as listed by the manufacturer: It is used to control blood glucose (sugar) in patients with Type II diabetes mellitus.

How it works: It is used when diet and exercise are not enough to control your blood glucose properly. It lowers blood glucose by increasing the amount of insulin (a hormone that controls blood glucose levels) produced by your pancreas.

Active ingredient: Gliclazide.

Reported side effects: Gastro-intestinal: Abdominal pain, anal fissure, appetite increased, colitis, duodenal ulcer, epigastric fullness, faecal incontinence, flatulence, gastric irritation, gastroesophageal reflux, GI neoplasm benign, hemorrhoids, melena, dry mouth, oesophagitis, saliva increased, tooth ache, tooth disorder, vomiting. These reactions are generally dose-related and may disappear when the dose is reduced. Hearing and vestibular: hearing decreased, tinnitus. Liver and biliary: increased liver enzymes, hepatitis, hepatomegaly. Metabolic and nutritional: gout, glycosuria, hypercholesterolemia, hypertriglyceridemia, thirst. Cases of hepatic porphyria and disulfiram-like reactions have been described with sulfonylurea drugs. Clinical experience to date has shown that gliclazide 80 mg tablets has a low incidence of disulfiram type reactions. Musculo-skeletal: arthropathy, bursitis, hernia congenital, skeletal pain, spine malformation.

Known drug interactions: Long-acting sulfonamides, tuberculostatics, NSAIDs, fibrates, monoamine oxidase inhibitors, salicylates, probenecid, beta-blockers, azole antifungal agents (oral and parenteral preparations), H2 receptor antagonists and angiotensin converting enzyme inhibitors , other antidiabetic agents (insulin, alpha glucosidase inhibitors, biguanides) , diuretics (thiazides, furosemide), corticosteroids, oral contraceptives (estrogen plus progestogen), chlorpromazine, ritodrine, salbutamol, terbutaline and nicotinic acid , Miconazole , Phenylbutazone , MAOIs , Chlorpromazine (neuroleptic agent) .

Maturity-onset diabetes : Adults : 40-80mg daily increasing if necessary to max 320mg daily. Doses above 160mg should be taken in two divided doses. Type 2 diabetes : Adults : 30-120mg depending on response, once daily with breakfast, including eldrely or those with renal failure. Children : Not recommended. OR As directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Gliclazide. Labelled strength: 60mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Diamicron Pharma (Pvt) Ltd.. Country of origin: Switzerland.