Galvus Met Tablets 501000mg 30s

What it is used for: Diabetes.

Indications as listed by the manufacturer: Vildagliptin + Metformin HCl is indicated for the treatment of patients with Type 2 diabetes mellitus (T2DM). Vildagliptin + Metformin HCl is indicated as an adjunct to diet and exercise to improve glycemic control in patients whose diabetes is not adequately controlled on metformin HCl alone or who are already treated with the combination of vildagliptin and metformin HCl, as separate tablets.

How it works: The administration of vildagliptin results in a rapid and complete inhibition of DPP-4 activity, resulting in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide). Metformin HCl decreases hepatic glucose production through inhibition of gluconeogenesis and glycogenolysis, decrease intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Active ingredient: Vildagliptin + Metformin HCl.

Reported side effects: Hypoglycemia, tremor, headache, dizziness & nausea , Fatigue , Hypoglycemia, dizziness, tremor, hyperhidrosis & asthenia , Decreased blood glucose, headache, chills, nausea, gastro-esophageal reflux disease , diarrhea & flatulence.

Known drug interactions: Thiazides, corticosteroids, thyroid products and sympathomimetics , Furosemide , Nifedipine , Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin) , estrogens, oral contraceptives, phenytoin, nicotinic acid , alcohol.

Based on the patient's current dose of metformin HCl, Vildagliptin + Metformin HCl may be initiated at either the 50mg + 500mg, 50mg + 850mg or 50mg + 1000mg tablet twice daily, one tablet in the morning and one tablet in the evening. Vildagliptin + Metformin HCl should be given with meals to reduce the gastrointestinal side effects associated with metformin HCl. When using Vildagliptin + Metformin HCl the maximum daily dose of vildagliptin (100mg) should not be exceeded. Children : Not Recommended.

Active ingredient: Vildagliptin + Metformin HCl. Labelled strength: 1000mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Galvus Pharmaceuticals (Pvt) Ltd.. Country of origin: Pakistan.