Sandimmun Neoral Capsules 100mg 50s

What it is used for: Immunosuppresant.

Indications as listed by the manufacturer: It contains the active substance ciclosporin. This belongs to a group of medicines known as immunosuppressive agents. These medicines are used to lower the body’s immune reactions.

How it works: If you have had an organ transplant, bone marrow and stem cell transplantation, the function of cyclosporin is to control your body’s immune system. It prevents rejection of transplanted organs by blocking the development of certain cells which would normally attack the transplanted tissue. If you have an autoimmune disease, in which your body’s immune response attacks your body’s own cells, cyclosporin stops this immune reaction. Such diseases include eye problems which threaten your vision (endogenous uveitis, including Behçet's uveitis), severe cases of certain skin diseases (atopic dermatitis, or eczema and psoriasis), severe rheumatoid arthritis and a kidney disease called nephrotic syndrome.

Active ingredient: Cyclosporin.

Reported side effects: Very common: may affect more than 1 in 10 people : Kidney problems , High blood pressure , Headache , Shaking of your body which you cannot control , Excessive growth of body and facial hair , High level of lipids in your blood . If any of these affects you severely, tell your doctorCommon: may affect up to 1 in 10 people :Fits (seizures) , Liver problems , High level of sugar in your blood , Tiredness , Loss of appetite , Nausea (feeling sick), vomiting, abdominal discomfort/pain, diarrhoea , Excessive hair growth , Acne, hot flushes , Fever , Low level of white blood cells , Feeling numb or tingling , Pain in your muscles, muscle spasm , Stomach ulcer , Gum tissue overgrowing and covering your teeth , High level of uric acid or patassium in your blood, low levels of magnesium in your blood . If any of these affects you severely, tell your doctor

Known drug interactions: Tacrolimus , other immunosuppressants , barbiturates , carbamazepine , oxcarbazepine , primidone , phenytoin , griseofulvin , trimethoprim , rifampicin , octreotide , orlistat , St. John's Wort, macrolides , azole antifungals , calcium channel blockers , metoclopramide , oral contraceptives , danazol , allopurinol , amiodarone , ursodeoxycholic acid , protease inhibitors , imatinib , nephrotoxic drugs , NSAIDs , vaccines , digoxin , corticosteroids , statins , etoposide , colchicine , K+ sparing diuretics , K+ supplements , ACE inhibitors , angiotensin II antagonists , grapefruit juice , methotrexate , H2 blockers , propafenone , bromocriptine , doxycycline , chloroquine , sulfinpyrazone , terbinafine , bosentan , substrates of CYP3A4 and /or P-glycoprotein , repaglinide.

In adults: Organ, bone marrow and stem cell transplantation : The total dose each day is usually between 2 mg and 15 mg per kilogram body weight. This is divided in two doses. Usually, higher doses are used before and just after your transplant. Lower doses are used once your transplanted organ or bone marrow has stabilised. Your doctor will adjust your dose to one that is ideal for you. To do this, your doctor mayneed to do some blood tests. Endogenous uveitis : The total dose each day is usually between 5 mg and 7 mg per kilogram body weight. This is divided in two doses. Nephrotic syndrome : The total dose each day for adults is usually 5 mg per kilogram body weight. This is divided in two doses. In patients with kidney problems, the first dose taken each day should not be more than 2.5 mg per kilogram body weight. Severe rheumatoid arthritis : The total dose each day is usually between 3 mg per kilogram of your body weight and 5 mg per kilogram body weight. This is divided in two doses. Psoriasis and atopic dermatitis : The total dose each day is usually between 2.5 mg per kilogram of your body weight and 5 mg per kilogram body weight. This is divided in two doses. In children:Nephrotic syndrome : The total dose each day for children is usually 6 mg per kilogram body weight. This is divided in two doses. In patients with kidney problems, the first dose taken each day should not be more than 2.5 mg per kilogram body weight. Follow your doctor's instructions exactly and never change the dose yourself, even if you feel well.

Active ingredient: Cyclosporin. Labelled strength: 100mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Sandimmun Pharma (Pvt) Ltd.. Country of origin: Pakistan.