Lasix Tablets 20mg 2x50s

What it is used for: Heart Failure.

Indications as listed by the manufacturer: It is use in : ? Fluid retention associated with chronic congestive cardiac failure (if diuretic treatment is required). ? Fluid retention associated with acute congestive cardiac failure. ? Fluid retention associated with chronic renal failure. ? Maintenance of fluid excretion in acute renal failure, including that due to pregnancy or burns. ? Fluid retention associated with nephrotic syndrome (if diuretic treatment is required). ? Fluid retention associated with liver disease (if necessary to supplement treatment with aldosterone antagonists). ? Hypertension. ? Hypertensive crisis (as a supportive measure). ? Support of forced diuresis.

How it works: It has been demonstrated that Furosemide inhibits primarily the absorption of sodium and chloride not only in the proximal and distal tubules but also in the loop of Henle. The high degree of efficacy is largely due to the unique site of action. The action on the distal tubule is independent of any inhibitory effect on carbonic anhydrase and aldosterone.

Active ingredient: Furosemide.

Reported side effects: Gastrointestinal System Reaction : Hepatic encephalopathy in patients with oral and gastric irritation hepatocellular insufficiency , cramping , pancreatitis , diarrhea , jaundice (intrahepatic cholestatic jaundice) , constipation , increased liver enzymes , nausea , anorexia , vomiting ; Systemic Hypersensitivity Reactions : Severe anaphylactic or anaphylactoid , interstitial nephritis reactions (e.g. with shock) , necrotizing angiitis , systemic vasculitis ; Central Nervous System Reactions , tinnitus and hearing loss , dizziness , paresthesias , headache , vertigo , blurred vision , xanthopsia .

Known drug interactions: Aminoglycoside antibiotics , ethacrynic acid , cisplatin , tubocurarine , Lithium , angiotensin converting enzyme inhibitors or angiotensin II receptor blockers , norepinephrine , sucralfate , Phenytoin , Methotrexate , cephalosporin , cyclosporine .

Oedema : Adults : Treatment is usually begun with 20-80mg as single dose daily or an alternate days . Children : Usual : 2mg/kg as single dose , may increase by 1-2mg/kg after 6-8 hr . Max : 6mg/kg. Heart Failure : Adults : Usual : 20-80mg as a single dose , may repeat or increase by 20-40mg after 6-8hr . Max : 600mg/dday . Hypertension : Adults : Initial : 40mg twice daily . Maintenance : Adjust according to response . OR As directed by your physician .

Active ingredient: Furosemide. Labelled strength: 20mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Lasix Healthcare (Pvt) Ltd.. Country of origin: Germany.