Kelac 10mg Tablets 30s

What it is used for: Pain & Inflammation.

Indications as listed by the manufacturer: These are indicated for the short-term management of moderate to severe acute postoperative pain.

How it works: Ketorolac is a potent analgesic agent of the non-steroidal, anti-inflammatory class (NSAID). Its mode of action is to inhibit the cyclooxygenase enzyme system and hence prostaglandin synthesis and it demonstrates a minimal anti-inflammatory effect at its analgesic dose. Ketorolac is not an anesthetic agent and possesses no sedative or anxiolytic properties; therefore it is not recommended as a pre-operative medication for the support of anesthesia when these effects are required. It is not an opioid and, has no known effects on opioid receptors.

Active ingredient: Ketorolac Tromethamine.

Reported side effects: Gastrointestinal tract: abdominal discomfort, constipation, diarrhoea, dyspepsia, eructation, flatulence, fullness, gastritis, gastrointestinal bleeding, gastrointestinal pain, nausea, pancreatitis, peptic ulcer, perforation, stomatitis, vomiting. Central nervous/ musculoskeletal systems: abnormal dreams, abnormal taste and vision, abnormal thinking, aseptic meningitis, convulsions, depression, dizziness, drowsiness, dry mouth, euphoria, excessive thirst, functional disorders, hallucinations, headache, hearing loss, hyperkinesia, inability to concentrate, insomnia, myalgia, nervousness, paraesthesia, stimulation, sweating. Tinnitus, vertigo. Urinary tract and kidneys: acute renal failure, flank pain . Skin: exfoliative dermatitis, Lyell's syndrome, maculopapular rash, pruritus, Stevens-Johnson syndrome, urticaria. Hypersensitivity reactions: anaphylaxis, bronchospasm, flushing and rash, hypotension, laryngeal edema. Such reactions may occur in patients with or without known sensitivity to Ketor or other NSAIDs. Bleeding: epistaxis, hematomata, postoperative wound haemorrhage .

Known drug interactions: Morphine sulphate, pethidine hydrochloride, promethazine hydrochloride or hydroxyzine hydrochloride , Anticoagulants , lithium , NSAIDS , methotrexate , probenecid , aspirin , diuretics , mifepristone , cyclosporin , tacrolimus .

Adults: the recommended initial dose of Ketorolac is 10 mg, followed by 10-30 mg every 4 to 6 hours as required. In the initial postoperative period, Ketorolac may be given as often as every 2 hours if needed. The lowest effective dose should be given. A total daily dose of 90 mg for non-elderly and 60 mg for the elderly, renally-impaired patients and patients less than 50 kg should not be exceeded. Children: Safety and efficacy in children have not been established. Therefore, Ketorolac is contraindicated for use in children under 16 years of age .

Active ingredient: Ketorolac Tromethamine. Labelled strength: 10mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Kelac Laboratories (Pvt) Ltd.. Country of origin: India.