Glandin E 2 Vag Tablets 3mg 1s

What it is used for: Labour Inducer.

Indications as listed by the manufacturer: It is indicated for induction of labour, when there are no foetal or maternal contraindications.

How it works: Dinoprostone is a prostaglandin of the E series with actions on smooth muscle; the endogenous substance is termed prostaglandin E2. It induces contraction of uterine muscle at any stage of pregnancy and is reported to act predominantly as a vasodilator on blood vessels and as a bronchodilator on bronchial muscle. It is postulated that vaginal absorption of PGE2 stimulates endogenous PGE2 and PGF2a production, similar to that which is seen in spontaneous labour.

Active ingredient: Dinoprostone.

Reported side effects: Vomiting • Nausea • Diarrhoea • Sudden blockage of a blood vessel with amniotic fluid (the fluid which surrounds the baby) or by a blood clots in the lungs. This could cause chest pain and shortness of breath. • Placenta becoming detached • Foetal death, stillbirth and death of the newborn baby (neonatal death); especially following serious events such as tearing of the womb. • Abnormally strong, frequent or long contractions of the womb • Slowing or quickening of the baby’s heart rate and distress in the baby • Itching, soreness, rash or feeling of warmth of the vaginal area • High blood pressure in the mother

Known drug interactions: Oxytocin

Adults : By vagina, induction of labour, inserted high into posterior fornix; 3mg, followed after 6-8hr by 3mg if labour is not established ; max 6mg (vaginal tab/pessary) Children : Not applicable. OR As directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Dinoprostone. Labelled strength: 3mg.

Store in a refrigerator (2°C–8°C). Do not Freeze .

Manufactured by Glandin Laboratories (Pvt) Ltd.. Country of origin: Pakistan.