Exelon 3mg Capsules 28s

What it is used for: Alzheimer.

Indications as listed by the manufacturer: Treatment of patients with mild to moderately severe dementia of the Alzheimer type, also termed probable Alzheimer’s Disease or Alzheimer’s Disease. Treatment of patients with mild to moderately severe dementia associated with Parkinson’s disease.

How it works: Pathological changes in dementia such as Alzheimerâs Disease involve cholinergic neuronal pathways that project from the basal forebrain to the cerebral cortex and hippocampus. These pathways are known to be involved in attention, learning and memory and other cognitive processes. Rivastigmine, a brain-selective acetyl- and butyryl-cholinesterase inhibitor of the carbamate type, is thought to facilitate cholinergic neurotransmission by slowing the degradation of acetylcholine released by functionally intact cholinergic neurons. Data from animal studies indicate that rivastigmine selectively increases the availability of acetylcholine in the cortex and hippocampus. Thus, Exelon may have an ameliorative effect on cholinergicmediated cognitive deficits associated with Alzheimerâs Disease and with Parkinsonâs disease. In addition, there is some evidence that cholinesterase inhibition could slow the formation of amyloidogenic beta-amyloid-precursor protein (APP) fragments, and thus of amyloid plaques, which are one of the main pathological features of Alzheimerâ

Active ingredient: Rivastigmine.

Reported side effects: Feeling dizzy • Loss of appetite • Stomach problems such as feeling sick (nausea) or being sick (vomiting), diarrhoea • Anxiety • Sweating • Headache • Heartburn • Weight loss • Stomach pain • Feeling agitated • Drowsiness • Feeling tired or weak • Generally feeling unwell • Trembling or feeling confused Nightmares .

Known drug interactions: Metoclopramide , oxybutynin, tolterodine , Succinylcholine-type muscle relaxants , beta-blockers (including atenolol) , nicotine.

Adult : Initial dose is 1.5 mg twice a day. Patients known to be particularly sensitive to the effects of cholinergic drugs should be started at a dose of 1 mg twice a day ; Maintenance dose : 1.5 mg to 6 mg twice a day. Recommended maximum daily dose 6 mg twice a day. Children and adolescents (age below 18 years): The use of Rivastigmine in children has not been studied and is therefore not recommended. Always ask your physician or pharmacist for dose adjustments.

Active ingredient: Rivastigmine. Labelled strength: 3mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Exelon Pharmaceuticals (Pvt) Ltd.. Country of origin: Pakistan.