Epan 20 Tablets

What it is used for: Bacterial Infection.

Indications as listed by the manufacturer: Cefixime is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: - Uncomplicated urinary tract infections - Otitis media - Pharyngitis and tonsillitis - Acute bronchitis and acute exacerbations of chronic bronchitis - Uncomplicated gonorrhea (cervical/urethral).

How it works: Like other cephalosporins, cefixime exhibits its bactericidal action by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis.

Active ingredient: Cefixime.

Reported side effects: Diarrhea (if severe diarrhea occurs, cefixime should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, Headache, dizziness, seizures , Transient rises in liver transaminases,alkaline phosphatase and jaundice , elevation of serum amylase.

Known drug interactions: Anticoagulants , Carbamazepine , probenecid.

The recommended adult dose of (Cefixime) is 200 - 400mg daily according to the severity of infection, given either as a single dose or in two divided doses. Children : 6-12mg/kg/day in two divided doses. Lower Respiratory Infection : Adults & Children : >12 yr or >50 kg : 400 mg once daily or 200 mg every 12 hr. <50 kg or > 6 mnth : 8 mg/kg once daily or 4 mg/kg every 12 hr. Otitis Media : Adults : Adults & Children : >12 yr ot >50 kg : 400 mg once daily or 200 mg every 12 hr . <50 kg or 6 mnth : 8 mg/kg once daily or 4 mg/kg every 12 hr. Always consult your doctor or pharmacist for dose adjustments.

Active ingredient: Cefixime.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Epan Laboratories (Pvt) Ltd.. Country of origin: Switzerland.