Diuza 25mg Tablets 30s

What it is used for: Hypertension.

Indications as listed by the manufacturer: It is used to treat : High blood pressure ; fluid retention in the body (oedema).

How it works: Hydrochlorothiazide is a diuretic and antihypertensive drug. The reduction in the blood pressure is partly due to the diuretic effect, but probably also that some of the blood vessels (arterioles) are widened and hereby the resistance in the blood vessels are lowered.

Active ingredient: Hydrochlorothiazide.

Reported side effects: Disturbances in the electrolyte and fluid imbalance, especially reduced potassium, sodium, magnesium and chloride levels and raised calcium levels in the blood (hypokalaemia, hyponatraemia, hypochloraemia and hypercalcaemia) - raised blood sugar levels (hyperglycaemia) and increased excretion of sugar in the urine (glucosuria) - raised uric acid levels (hyperuricaemia), which may lead to attacks of gout in predisposed patients - increase in blood lipids (cholesterol, triglycerides) , reduction in blood platelets (thrombocytopenia, sometimes with purpura) - feeling of increased heart rate (palpitations) - loss of appetite - gastrointestinal complaints (e.g. nausea, vomiting, diarrhoea, pains and cramps in the abdominal cavity) - temporary increase in urinary excreted substances (creatinine, urea).

Known drug interactions: Lithium ,furosemide , laxatives (e.g. castor oil), corticosteroids (e.g. prednisone), ACTH (a hormone), amphotericin, carbenoxolone , penicillin G sodium , salicylic acid and derivatives , digoxin , quinidine, disopyramide, amiodarone, sotalol , thioridazine, chlorpromazine, levomepromazine , sparfloxacine, pentamidine terfenadine captopril, enalapril and betablockers, nitrates, barbiturates, phenothiazines, tricyclic antidepressives, insulins or oral agents such as metformin Amantadine , Atropine , biperiden - Cholestyramine and colestipol, Vitamin D and/or calcium supplements , corticosteroids, carbamazepine , cyclosporine .

Adults : High blood pressure : The recommended initial dose is 12.5 to 50 mg/day. Oedema : The recommended initial dose is 25–50 mg/day or in severe cases 75–100 mg/day .Children : Oedema and hypertension : <6mnth , 1-2mg/kg/day in 1-2 divided doses ; 6mnth-2yr , 1-3mg/kg/day in 2 divided doses , max 37.5mg/day ; 2-18yr , 1-2mg/kg/day , max 3mg/kg/day (50mg/day) . Or As directed by your physician.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Hydrochlorothiazide. Labelled strength: 25mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Diuza Pharmaceuticals (Pvt) Ltd.. Country of origin: Germany.