Deltoin 100mg Tablets 100s

What it is used for: Epilepsy.

Indications as listed by the manufacturer: Oral : Epilepsy particularly of the grand mal type and psychomotor seizures . Migraine & trigeminal neuralgia . Inj : Status epilepticus , seizures in neurosurgery .

How it works: Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels. This blocks sustained high frequency repetitive firing of action potentials.

Active ingredient: Phenytoin Sodium.

Reported side effects: Bruising, fever , Skin rash, fever, swollen glands, increase in a type of white blood cell (eosinophilia), and inflammation of internal organs (liver, lungs, heart, kidneys and large intestine), Sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, rash or itching (especially affecting the whole body). There is a higher incidence of this in black patients. If you develop potentially life-threatening skin rashes that causes blistering (this can affect the mouth and tongue). These may be signs of a condition known as Stevens Johnson Syndrome, or toxic epidermal necrolysis (TEN). These have been reported very rarely.

Known drug interactions: Medicines used for heart and circulation problems (e.g. dicoumarol, amiodarone, reserpine, digitoxin, digoxin, mexiletine, nisoldipine, furosemide, quinidine, warfarin and calcium channel blockers including diltiazem and nifedipine) - Medicines used for epilepsy (e.g. carbamazepine, lamotrigine, phenobarbital, sodium valproate, valproic acid, oxcarbazepine, topiramate, succinimides including ethosuximide, and vigabatrin) - Medicines used to treat fungal infections (e.g. amphotericin B, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, miconazole) - Medicines used for tuberculosis and other infections (e.g. chloramphenicol, isoniazid, rifampicin, sulfonamides, sulfadiazine, sulfamethizole, sulfamethoxazole-trimethoprim, sulfaphenazole, sulfisoxazole, doxycycline, ciprofloxacin) - Medicines used for stomach ulcers (e.g. omeprazole, sucralfate and the medicines known as H2 antagonists including cimetidine, ranitidine, famotidine and some antacids) - Medicines used for asthma and bronchitis (e.g. theophylline) - Medicines used for pain and inflammation (e.g. phenylbutazone, propoxyphene, salicylates including aspirin and steroids) .

Adults : ORAL : 100mg two or four times before meals with max total of 600mg daily . Titrate : Every 7-10 days . May give once daily if controlled on 300mg/day . INJECTION : By slow IV injection or infusion ( with blood pressure and ECG monitoring ) . Status Epilepticus : 18mg/kg at a rate not exceeding 50mg per min , as a loading dose ; maintenance doses of about 100mg should be given thereafter at intervals of every 6-8hr , monitored by measurement of plasma concentrations; rate and dose reduced acc.to weight. OR As directed by your physician.

Active ingredient: Phenytoin Sodium. Labelled strength: 100mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Deltoin Healthcare (Pvt) Ltd.. Country of origin: United Kingdom.