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Highnoon Labs
Genthro 500mg Tablets 6s
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Pfizer
Bysilol 10mg Tablets 14s
Rated 4.0 out of 5 (34)SKU HP-02885
A tablet containing Nebivolol HCl, indicated for Hypertension.
Rs. 1,445Rs. 1,520-5%
You save Rs. 75
60 Capsules
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Quantity
Bysilol 10mg Tablets 14s quantity: 1
- 100% authentic
- Free over Rs. 1,500
- Pharmacist verified
- 7-day returns
Total for 1 pack: Rs. 1,445
What it is used for: Hypertension.
Indications as listed by the manufacturer: For the treatment of essential hypertension, stable, mild and moderate chronic heart failure in addition to standard therapies in elderly patients 70 years and may be used alone or in combination with other anti-hypertensive agents.
How it works: Nebivolol is a ß1 selective adrenoceptor antagonist whose hemodynamic effects differ from those of classical ß-adrenoceptor antagonist as a result of a vasodilating action. It has mild vasodilating properties attributed to its interaction with the L-arginine/nitric oxide path way, a property not shared by other ß-blockers. Nebivolol lacks intrinsic sympathomimetic and membrane stabilizing activity at therapeutically relevant concentrations. At clinically relevant doses, nebivolol does not demonstrate a1-adrenergic receptor blockade activity.
Active ingredient: Nebivolol HCl.
Reported side effects: Common: Headache, dizziness, paresthesia, dyspnea, constipation, nausea, diarrhea, tiredness, edema. Uncommon: Nightmares, depression, impaired vision, bradycardia, heart failure, slowed AV conduction/AV-block, hypotension, (increase of) intermittent claudication, bronchospasm, dyspepsia, flatulence, vomiting, pruritus, rash, erythematous, impotence. Rare: Syncope, psoriasis aggravated.
Known drug interactions: Phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes) or antiarrhythmic agents such as disopyramide , digitalis glycosides and ß-blockers , reserpine or guanethidine , clonidine , CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine ) , Cimetidine , Sildenafil.
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Free pharmacist advice on interactions and timing — call or ask at checkout
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
Hypertension - Adults : The dose is one tablet (5mg) daily, preferably at the same time of the day. Tablets may be taken with or without meals. The initial up titration should be done at 1-2 weekly intervals based on patient tolerability. The maximum recommended dose is 10mg nebivolol once daily . Elderly : In patients over 65 years, the recommended starting dose is 2.5mg daily. If needed, the daily dose may be increased to 5mg. Children : Not recommended. Or As directed by your physician.
Active ingredient: Nebivolol HCl. Labelled strength: 10mg.
- Nebivolol is contraindicated in patients with:- Hypersensitivity to the active substance or to any of the components.- Severe hepatic insufficiency.- Acute heart failure, cardiogenic shock or episodes of heart failure decompensation requiring I.V. inotropic therapy.- Sick sinus syndrome, including sino-atrial block.- Second and third degree heart block (without a pacemaker).- History of bronchospasm and bronchial asthma.- Untreated phaeochromocytoma.- Metabolic acidosis.- Bradycardia (heart rate < 60bpm prior to start of therapy).- Hypotension (systoli c blood pressure < 90mmHg).- Severe peripheral circulatory disturbances.
- Care should be taken in diabetic patients however, as nebivolol may mask certain symptoms of hypoglycemia (tachycardia, palpitations). ß-adrenergic blocking agents may mask tachycardic symptoms in hyperthyroidism. Abrupt withdrawal may intensify symptoms.
- The treatment with nebivolol is not recommended to be stopped abruptly since this might lead to a transitory worsening of heart failure. If discontinuation is necessary, the dose should be gradually decreaseddivided into halves weekly. If the angina worsens or acute coronary insufficiency develops, it is recommended that nebivolol be promptly reinstituted, at least temporarily.
- ß-blockers can precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular diseases. Caution should be exercised in these patients.
- In patients who have compensated congestive heart failure, nebivolol should be administered cautiously. If heart failure worsens, discontinuation of nebivolol should be considered.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Bysilol Pharma (Pvt) Ltd.. Country of origin: United Arab Emirates.
4.0
Rated 4.0 out of 534 verified ratings
- 5★0%
- 4★80%
- 3★20%
- 2★0%
- 1★0%
- Usman TariqVerified Purchase4 Aug 2026Rated 4.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
- Adnan YousufVerified Purchase24 Jul 2026Rated 4.0 out of 5
Does the job, though the pack is smaller than I expected — worth checking the size before ordering.
- Komal J.Verified Purchase11 Jul 2026Rated 4.0 out of 5
Second time ordering. Batch and expiry were printed clearly and matched what the site listed.
- Nadia IqbalVerified Purchase7 Jul 2026Rated 3.0 out of 5
The product is genuine but did not suit me personally. Customer service handled the return without any argument.
- Fatima S.25 Jun 2026Rated 4.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
What it is used for: Hypertension.
Indications as listed by the manufacturer: For the treatment of essential hypertension, stable, mild and moderate chronic heart failure in addition to standard therapies in elderly patients 70 years and may be used alone or in combination with other anti-hypertensive agents.
How it works: Nebivolol is a ß1 selective adrenoceptor antagonist whose hemodynamic effects differ from those of classical ß-adrenoceptor antagonist as a result of a vasodilating action. It has mild vasodilating properties attributed to its interaction with the L-arginine/nitric oxide path way, a property not shared by other ß-blockers. Nebivolol lacks intrinsic sympathomimetic and membrane stabilizing activity at therapeutically relevant concentrations. At clinically relevant doses, nebivolol does not demonstrate a1-adrenergic receptor blockade activity.
Active ingredient: Nebivolol HCl.
Reported side effects: Common: Headache, dizziness, paresthesia, dyspnea, constipation, nausea, diarrhea, tiredness, edema. Uncommon: Nightmares, depression, impaired vision, bradycardia, heart failure, slowed AV conduction/AV-block, hypotension, (increase of) intermittent claudication, bronchospasm, dyspepsia, flatulence, vomiting, pruritus, rash, erythematous, impotence. Rare: Syncope, psoriasis aggravated.
Known drug interactions: Phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes) or antiarrhythmic agents such as disopyramide , digitalis glycosides and ß-blockers , reserpine or guanethidine , clonidine , CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine ) , Cimetidine , Sildenafil.
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Free pharmacist advice on interactions and timing — call or ask at checkout
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
Hypertension - Adults : The dose is one tablet (5mg) daily, preferably at the same time of the day. Tablets may be taken with or without meals. The initial up titration should be done at 1-2 weekly intervals based on patient tolerability. The maximum recommended dose is 10mg nebivolol once daily . Elderly : In patients over 65 years, the recommended starting dose is 2.5mg daily. If needed, the daily dose may be increased to 5mg. Children : Not recommended. Or As directed by your physician.
Active ingredient: Nebivolol HCl. Labelled strength: 10mg.
- Nebivolol is contraindicated in patients with:- Hypersensitivity to the active substance or to any of the components.- Severe hepatic insufficiency.- Acute heart failure, cardiogenic shock or episodes of heart failure decompensation requiring I.V. inotropic therapy.- Sick sinus syndrome, including sino-atrial block.- Second and third degree heart block (without a pacemaker).- History of bronchospasm and bronchial asthma.- Untreated phaeochromocytoma.- Metabolic acidosis.- Bradycardia (heart rate < 60bpm prior to start of therapy).- Hypotension (systoli c blood pressure < 90mmHg).- Severe peripheral circulatory disturbances.
- Care should be taken in diabetic patients however, as nebivolol may mask certain symptoms of hypoglycemia (tachycardia, palpitations). ß-adrenergic blocking agents may mask tachycardic symptoms in hyperthyroidism. Abrupt withdrawal may intensify symptoms.
- The treatment with nebivolol is not recommended to be stopped abruptly since this might lead to a transitory worsening of heart failure. If discontinuation is necessary, the dose should be gradually decreaseddivided into halves weekly. If the angina worsens or acute coronary insufficiency develops, it is recommended that nebivolol be promptly reinstituted, at least temporarily.
- ß-blockers can precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular diseases. Caution should be exercised in these patients.
- In patients who have compensated congestive heart failure, nebivolol should be administered cautiously. If heart failure worsens, discontinuation of nebivolol should be considered.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Bysilol Pharma (Pvt) Ltd.. Country of origin: United Arab Emirates.
4.0
Rated 4.0 out of 534 verified ratings
- 5★0%
- 4★80%
- 3★20%
- 2★0%
- 1★0%
- Usman TariqVerified Purchase4 Aug 2026Rated 4.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
- Adnan YousufVerified Purchase24 Jul 2026Rated 4.0 out of 5
Does the job, though the pack is smaller than I expected — worth checking the size before ordering.
- Komal J.Verified Purchase11 Jul 2026Rated 4.0 out of 5
Second time ordering. Batch and expiry were printed clearly and matched what the site listed.
- Nadia IqbalVerified Purchase7 Jul 2026Rated 3.0 out of 5
The product is genuine but did not suit me personally. Customer service handled the return without any argument.
- Fatima S.25 Jun 2026Rated 4.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
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Bundle total
Rs. 4,430Rs. 4,750
Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.
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