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Highnoon Labs
Genthro 500mg Tablets 6s
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Searle
Bosmon Tablets 62/5mg 14s
Rated 4.5 out of 5 (17)SKU HP-02568
A tablet containing Bosentan Monohydrate, indicated for Hypertension.
Rs. 1,400Rs. 1,750-20%
You save Rs. 350
60ml Drops
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Quantity
Bosmon Tablets 62/5mg 14s quantity: 1
- 100% authentic
- Free over Rs. 1,500
- Pharmacist verified
- 7-day returns
Total for 1 pack: Rs. 1,400
What it is used for: Hypertension.
Indications as listed by the manufacturer: It is indicated for the treatment of pulmonary arterial hypertension in patients with WHO functional class III or IV primary pulmonary hypertension, or pulmonary hypertension secondary to scleroderma or congenital heart disease or human immunodeficiency virus in patients who did not respond adequately to conventional therapy .
How it works: Bosentan is a dual endothelin receptor antagonist with affinity for both ETA and ETB receptors. Bosentan decreases both pulmonary and systemic vascular resistance, resulting in increased cardiac output without increasing heart rate. The neurohormone endothelin is a potent vasoconstrictor with the ability to promote fibrosis, cell proliferation, and tissue remodeling. Endothelin concentrations in plasma and tissues are increased in a number of cardiovascular disorders, including pulmonary hypertension, suggesting a pathological role for endothelin in these diseases. In pulmonary arterial hypertension, endothelin plasma concentrations strongly correlate with poor prognosis .
Active ingredient: Bosentan Monohydrate.
Reported side effects: Flushed appearance or redness of skin ; Hypersensitivity reactions (including skin inflammation, itching and rash) ; Gastrooesophageal reflux disease (acid reflux) ; Diarrhoea ; Stuffy or blocked nose ; Syncope (fainting) ; Palpitations (fast or irregular heart beats) ; Low blood pressure .
Known drug interactions: Warfarin , Simvastatin and Other Statins , Glyburide , Ketoconazole , Cyclosporine A , Tacrolimus and Sirolimus , Sildenafil , Tadalafil , Rifampicin , Epoprostenol , Antiretroviral Agents: Lopinavir + Ritonavir .
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Prescription verified by a pharmacist before your order is dispatched
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
Adults : The treatment in adults is usually started for the first 4 weeks with the recommended dose of 62.5 mg twice daily (morning and evening), from then your doctor will usually advise you to take a 125 mg tablet twice daily, depending on how you react to Bosentan. Use in children and adolescents : The dose recommendation in children is only for the treatment of pulmonary arterial hypertension. For children 1 year and older, the recommended dose for treatment with bosentan is usually started with 2 mg per kg of body weight twice daily (morning and evening). OR As directed by your physician.
Active ingredient: Bosentan Monohydrate. Labelled strength: 62.5mg.
- It is contraindicated in patients: Who are hypersensitive to bosentan or to any excipient in the formulation ; Who are pregnant, or of childbearing potential unless adequate contraceptive measures are taken. Fetal malformations were reported in animals .
- The efficacy of bosentan has not been established in patients with severe Pulmonary arterial hypertension (PAH). Transfer to a therapy that is recommended at the severe stage of the disease (e.g. epoprostenol) should be considered if the clinical condition deteriorates .
- Bosentan should only be initiated if the systemic systolic blood pressure is higher than 85 mmHg.
- Bosentan has not been shown to have a beneficial effect on the healing of existing digital ulcers.
- Cases of pulmonary edema have been reported with vasodilators (mainly prostacyclins) when used in patients with pulmonary veno-occlusive disease. Consequently, should signs of pulmonary edema occur when Bosentan is administered in patients with Pulmonary arterial hypertension (PAH) , the possibility of associated veno-occlusive disease should be considered.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Bosmon Pharma (Pvt) Ltd.. Country of origin: Pakistan.
4.5
Rated 4.5 out of 517 verified ratings
- 5★63%
- 4★38%
- 3★0%
- 2★0%
- 1★0%
- Imran Q.4 Aug 2026Rated 5.0 out of 5
Arrived in a plain bag, nothing written on the outside. Good for something you would rather not advertise.
- Faisal Sheikh23 Jul 2026Rated 4.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Nadia IqbalVerified Purchase11 Jul 2026Rated 5.0 out of 5
Exactly what my doctor prescribed. The pharmacist called to confirm the strength before dispatch, which I appreciated.
- Bilal AhmedVerified Purchase5 Jul 2026Rated 5.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Rabia N.17 Jun 2026Rated 5.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
- Adnan YousufVerified Purchase5 Jun 2026Rated 4.0 out of 5
Genuine product, sealed and well within expiry. Delivery reached Lahore the next day.
- Usman TariqVerified Purchase26 May 2026Rated 5.0 out of 5
Rider was on time and the item was properly bubble-wrapped. No complaints.
- Sana MalikVerified Purchase12 May 2026Rated 4.0 out of 5
Rider was on time and the item was properly bubble-wrapped. No complaints.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
What it is used for: Hypertension.
Indications as listed by the manufacturer: It is indicated for the treatment of pulmonary arterial hypertension in patients with WHO functional class III or IV primary pulmonary hypertension, or pulmonary hypertension secondary to scleroderma or congenital heart disease or human immunodeficiency virus in patients who did not respond adequately to conventional therapy .
How it works: Bosentan is a dual endothelin receptor antagonist with affinity for both ETA and ETB receptors. Bosentan decreases both pulmonary and systemic vascular resistance, resulting in increased cardiac output without increasing heart rate. The neurohormone endothelin is a potent vasoconstrictor with the ability to promote fibrosis, cell proliferation, and tissue remodeling. Endothelin concentrations in plasma and tissues are increased in a number of cardiovascular disorders, including pulmonary hypertension, suggesting a pathological role for endothelin in these diseases. In pulmonary arterial hypertension, endothelin plasma concentrations strongly correlate with poor prognosis .
Active ingredient: Bosentan Monohydrate.
Reported side effects: Flushed appearance or redness of skin ; Hypersensitivity reactions (including skin inflammation, itching and rash) ; Gastrooesophageal reflux disease (acid reflux) ; Diarrhoea ; Stuffy or blocked nose ; Syncope (fainting) ; Palpitations (fast or irregular heart beats) ; Low blood pressure .
Known drug interactions: Warfarin , Simvastatin and Other Statins , Glyburide , Ketoconazole , Cyclosporine A , Tacrolimus and Sirolimus , Sildenafil , Tadalafil , Rifampicin , Epoprostenol , Antiretroviral Agents: Lopinavir + Ritonavir .
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Prescription verified by a pharmacist before your order is dispatched
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
Adults : The treatment in adults is usually started for the first 4 weeks with the recommended dose of 62.5 mg twice daily (morning and evening), from then your doctor will usually advise you to take a 125 mg tablet twice daily, depending on how you react to Bosentan. Use in children and adolescents : The dose recommendation in children is only for the treatment of pulmonary arterial hypertension. For children 1 year and older, the recommended dose for treatment with bosentan is usually started with 2 mg per kg of body weight twice daily (morning and evening). OR As directed by your physician.
Active ingredient: Bosentan Monohydrate. Labelled strength: 62.5mg.
- It is contraindicated in patients: Who are hypersensitive to bosentan or to any excipient in the formulation ; Who are pregnant, or of childbearing potential unless adequate contraceptive measures are taken. Fetal malformations were reported in animals .
- The efficacy of bosentan has not been established in patients with severe Pulmonary arterial hypertension (PAH). Transfer to a therapy that is recommended at the severe stage of the disease (e.g. epoprostenol) should be considered if the clinical condition deteriorates .
- Bosentan should only be initiated if the systemic systolic blood pressure is higher than 85 mmHg.
- Bosentan has not been shown to have a beneficial effect on the healing of existing digital ulcers.
- Cases of pulmonary edema have been reported with vasodilators (mainly prostacyclins) when used in patients with pulmonary veno-occlusive disease. Consequently, should signs of pulmonary edema occur when Bosentan is administered in patients with Pulmonary arterial hypertension (PAH) , the possibility of associated veno-occlusive disease should be considered.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Bosmon Pharma (Pvt) Ltd.. Country of origin: Pakistan.
4.5
Rated 4.5 out of 517 verified ratings
- 5★63%
- 4★38%
- 3★0%
- 2★0%
- 1★0%
- Imran Q.4 Aug 2026Rated 5.0 out of 5
Arrived in a plain bag, nothing written on the outside. Good for something you would rather not advertise.
- Faisal Sheikh23 Jul 2026Rated 4.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Nadia IqbalVerified Purchase11 Jul 2026Rated 5.0 out of 5
Exactly what my doctor prescribed. The pharmacist called to confirm the strength before dispatch, which I appreciated.
- Bilal AhmedVerified Purchase5 Jul 2026Rated 5.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Rabia N.17 Jun 2026Rated 5.0 out of 5
Been using this for a few months now. Ordering here is cheaper than my local shop and the packing is always careful.
- Adnan YousufVerified Purchase5 Jun 2026Rated 4.0 out of 5
Genuine product, sealed and well within expiry. Delivery reached Lahore the next day.
- Usman TariqVerified Purchase26 May 2026Rated 5.0 out of 5
Rider was on time and the item was properly bubble-wrapped. No complaints.
- Sana MalikVerified Purchase12 May 2026Rated 4.0 out of 5
Rider was on time and the item was properly bubble-wrapped. No complaints.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
Frequently bought together
SearleBosmon Tablets 62/5mg 14sRs. 1,400Rated 4.5 out of 5
StandpharmXiga 5mg Tablets 14sRs. 1,595Rated 4.5 out of 5
Martin DowAldactone Tablets 100mg 10sRs. 1,390Rated 4.5 out of 5
Bundle total
Rs. 4,385Rs. 4,980
Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.
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