Biocobal 500mcg Injection 10s

What it is used for: Anaemia.

Indications as listed by the manufacturer: Mecobalamin is indicated for the treatment of: 1. Peripheral neuropathies. 2. Megaloblastic anemia caused by vitamin B12 deficiency.

How it works: 1. Mecobalamin is the one and only homologue of Vitamin B12 found in the brain that participates in transmethylation. Mecobalamin is well transported to nerve cell organelles than cyanocobalamin and plays the role of coenzyme in the synthesis of methionine from homocysteine. It is also involved in the synthesis of thymidine from deoxyuridine thus promoting nucleic acid protein synthesis.2. Mecobalamin normalizes axonal transport of skeletal protein in sciatic nerve cells. It exhibits neuropathologically and electrophysiologically inhibitory effects on nerve degeneration in neuropathies induced by drugs such as adriamycin, acrylamide and vincristine.

Active ingredient: Mecobalamin.

Reported side effects: Generally mecobalamin is well tolerated. However a few side effects like GI discomfort (including anorexia, nausea or diarrhea) and rash may be seen.

Known drug interactions: Neomycin, aminosalicylic acid, H2-blockers and colchicine , oral contraceptives , parenteral chloramphenicol.

ORAL : Adults - 500mcg 3 times daily. Children : Not Recommended. INJ : Adults : Peripheral neuropathies : 1 amp by IM or IV inj three times a week. Megaloblastic anemia : 1 amp by IM or IV inj three times a wk. After two month 1 amp in a single administration at 1 to 3 month intervals for maintenance therapy. Children : Not Recommended. OR As directed by your physician.

Active ingredient: Mecobalamin. Labelled strength: 500mcg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Biocobal Pharma (Pvt) Ltd.. Country of origin: Switzerland.