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OBS

Basoquin Tablets 150mg 60x10s

A tablet containing Amodiaquine, indicated for Malaria.

Rs. 121Rs. 142-15%

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Basoquin Tablets 150mg 60x10s quantity: 1
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Total for 1 pack: Rs. 121

What it is used for: Malaria.

Indications as listed by the manufacturer: Amodiaquine (AQ) in combination with artesunate is indicated for the treatment of uncomplicated P. falciparum or P. vivax malaria and is considered to be effective against P. ovale, P. knowlesi and P. malariae.

How it works: Amodiaquine is a Mannich base 4-aminoquinoline that is similar in structure and mechanism of action to chloroquine. Amodiaquine is converted to its active metabolite desethylamodiaquine and is thought to act by accumulating inside the parasite food vacuole and interfering with haem detoxification. The drug also inhibits the glutathione-dependent destruction of ferriprotoporphyrin IX in the malaria parasite, resulting in the accumulation of this peptide, which is toxic for the parasite. Amodiaquine is effective against some parasite strains that are resistant to chloroquine, although some crossresistance exists .

Active ingredient: Amodiaquine.

Reported side effects: Abdominal discomfort, nausea, vomiting, headache, dizziness, blurring of vision, mental and physical weakness, and fatigue , itching, cardiovascular abnormalities, dyskinesia, ocular damage, neuromuscular disorders and hearing loss .

Known drug interactions: Increased plasma concentration and elevated liver enzyme activities when given in combination with efavirenz ; Decreased plasma concentration with nevirapine ; Increased risk for neutropenia with zidovudine-containing regimens and trimethoprim plus sulfamethoxazole ; Increased risk for cardiac events with anti-arrhythmic agents ; Visual loss or disturbances with mefloquine ; Recommended to use with caution with inhibitors of CYP2C8 and CYP2A6 ; Amodiaquine may inhibit CYP2D6 and CYP2C9.

Frequently bought together

Bundle total

Rs. 3,106Rs. 3,372

Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.