Amtas Tablets 1040mg 14s

What it is used for: Hypertension.

Indications as listed by the manufacturer: It is indicated for the treatment of hypertension, alone or with other antihypertensive agents.

How it works: Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin by selectively blocking the binding of angiotensin to the AT1, receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin synthesis. Amlodipine: Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions by binding to both dihydropyridine and nondihydropyridine sites into vascular smooth muscle and cardiac muscle.

Active ingredient: Telmisartan + Amlodipine (As besylate).

Reported side effects: Telmisartan : Impotence, increased sweating, flushing; Body as a Whole: allergy, fever, leg pain, malaise , Palpitation, dependent edema, angina pectoris, tachycardia, leg edema, abnormal. ECG , insomnia, somnolence, migraine, vertigo, paresthesia, involuntary muscle contractions, hypoesthesia , flatulence, constipation, gastritis, vomiting, dry mouth, hemorrhoids, gastroenteritis, enteritis, gastroesophageal reflux, toothache, nonspecific gastrointestinal disorders , gout, hypercholesterolemia, diabetes mellitus . Amlodipine : Arrhythmia (including ventricular tachycardia and atrial fibrillation), bradycardia, chest pain, hypotension, peripheral ischemia, syncope, tachycardia, postural dizziness, postural hypotension, vasculitis , hypoesthesia, neuropathy peripheral, paresthesia, tremor, vertigo; Gastrointestinal: anorexia, constipation, dyspepsia, dysphagia, diarrhea, flatulence, pancreatitis, vomiting, gingival hyperplasia, change of bowel habit.

Known drug interactions: Baclofen, amifostine, neuroleptics or antidepressants , Corticosteroids , Potassium sparing diuretics or Potassium supplements , Lithium , acetyl salicylic acid , CYP3A4 inhibitors like erythromycin , diltiazem , ketoconazole, itraconazole, ritonavir , rifampicin, Hypericum perforatum .

Amlodipine + Telmisaratan is effective in the treatment of hypertension in once daily doses of amlodipine as 2.5mg to 10mg and telmisartan as 20mg to 80mg. It may be taken with or without food. Always consult your doctor or pharmacist for dose adjustment.

Follow your doctor’s instructions. The dosage above is the usual range — your prescription takes precedence over it.

Active ingredient: Telmisartan + Amlodipine (As besylate). Labelled strength: 40mg.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Amtas Healthcare (Pvt) Ltd.. Country of origin: Turkey.