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Highnoon Labs
Genthro 500mg Tablets 6s
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Searle
Agoviz 25mg Tablets 14s
Rated 4.0 out of 5 (37)SKU HP-00488
A tablet containing Agomelatine, indicated for Depression.
Rs. 2,135Rs. 2,510-15%
You save Rs. 375
60ml Drops
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Quantity
Agoviz 25mg Tablets 14s quantity: 1
- 100% authentic
- Free over Rs. 1,500
- Pharmacist verified
- 7-day returns
Total for 1 pack: Rs. 2,135
What it is used for: Depression.
Indications as listed by the manufacturer: Treatment of major depressive disorder in adults including prevention of relapse.
How it works: Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. Binding studies indicate that agomelatine has no effect on monoamine uptake and no affinity for a, ß adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors. Agomelatine resynchronizes circadian rhythms in circadian rhythm disruption. Agomelatine increases noradrenaline and dopamine release specifically in the frontal cortex and has no influence on the extracellular levels of serotonin .
Active ingredient: Agomelatine.
Reported side effects: Psychiatric disorders Common: Anxiety Uncommon: Agitation and related symptoms (such as irritability and restlessness), Aggression Nightmares, Abnormal dreams, confusional state Rare: Mania/hypomania, Hallucinations Frequency not known: Suicidal thoughts or behavior Nervous system disorders Common: Headache, Dizziness, Somnolence, Insomnia, Migraine Uncommon: Paraesthesia, Restless leg syndrome Rare: Akathisia Eyes disorders Uncommon: Blurred vision Ear and vestibular system disorders Uncommon: Tinnitus Gastrointestinal Disorders Common: Nausea, Diarrhoea, Constipation, Abdominal pain, vomiting Hepato- biliary disorders Common: Increased ALAT and/or ASAT Rare: Hepatitis, Increased gamma-glutamyltransferase (GGT) (>3 times the upper limit of the normal range), Increased alkaline phosphatase (>3 times the upper limit of the normal range), Hepatic failure Jaundice Skin and subcutaneous tissue disorders Common: Hyperhidrosis Uncommon: Eczema, Pruritus, Urticaria Rare: Erythematous rash, Face edema and angioedema Musculoskeletal and connective tissue disorders Common: Back pain General disorders and administration site conditions Common: Fatigue Renal and Urinary disorders Rare: Urinary retention
Known drug interactions: Potent CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin , moderate CYP1A2 inhibitors (e.g. propranolol, enoxacin ) .
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Prescription verified by a pharmacist before your order is dispatched
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
The recommended dose is 25 mg once daily taken orally at bedtime. After two weeks of treatment, if there is no improvement of symptoms, the dose may be increased to 50 mg once daily, i.e. two 25 mg tablets, taken together at bedtime. Or As directed by your physician.
Active ingredient: Agomelatine. Labelled strength: 25mg.
- Hypersensitivity to Agomelatine • Hepatic impairment (i.e. cirrhosis or active liver disease) or transaminases exceeding 3 times the upper limit of normal. • Concomitant use of potent CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin)
- Agomelatine should not be used for the treatment of major depressive episodes in elderly patients with dementia since the safety and efficacy of Agomelatine have not been established in these patients.
- Agomelatine should be used with caution in patients with a history of bipolar disorder, mania or hypomania and should be discontinued if a patient develops manic symptoms.
- Depression is associated with an increased risk of suicidal thoughts, self-harm and suicide (suicide-related events). This risk persists until significant remission occurs. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase in the early stages of recovery .
- Caution should be exercised when prescribing Agomelatine with moderate CYP1A2 inhibitors (e.g. propranolol, enoxacin) which may result in increased exposure of agomelatine.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Agoviz Laboratories (Pvt) Ltd.. Country of origin: United Arab Emirates.
4.0
Rated 4.0 out of 537 verified ratings
- 5★0%
- 4★75%
- 3★25%
- 2★0%
- 1★0%
- Adnan YousufVerified Purchase4 Aug 2026Rated 3.0 out of 5
Fine quality, wrong choice on my part — I should have asked the pharmacist first about the strength.
- Mehwish A.25 Jul 2026Rated 4.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Fatima S.Verified Purchase14 Jul 2026Rated 4.0 out of 5
Good value for the pack size. I compared prices across three sites before ordering.
- Ayesha K.Verified Purchase7 Jul 2026Rated 4.0 out of 5
Does the job, though the pack is smaller than I expected — worth checking the size before ordering.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
What it is used for: Depression.
Indications as listed by the manufacturer: Treatment of major depressive disorder in adults including prevention of relapse.
How it works: Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. Binding studies indicate that agomelatine has no effect on monoamine uptake and no affinity for a, ß adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors. Agomelatine resynchronizes circadian rhythms in circadian rhythm disruption. Agomelatine increases noradrenaline and dopamine release specifically in the frontal cortex and has no influence on the extracellular levels of serotonin .
Active ingredient: Agomelatine.
Reported side effects: Psychiatric disorders Common: Anxiety Uncommon: Agitation and related symptoms (such as irritability and restlessness), Aggression Nightmares, Abnormal dreams, confusional state Rare: Mania/hypomania, Hallucinations Frequency not known: Suicidal thoughts or behavior Nervous system disorders Common: Headache, Dizziness, Somnolence, Insomnia, Migraine Uncommon: Paraesthesia, Restless leg syndrome Rare: Akathisia Eyes disorders Uncommon: Blurred vision Ear and vestibular system disorders Uncommon: Tinnitus Gastrointestinal Disorders Common: Nausea, Diarrhoea, Constipation, Abdominal pain, vomiting Hepato- biliary disorders Common: Increased ALAT and/or ASAT Rare: Hepatitis, Increased gamma-glutamyltransferase (GGT) (>3 times the upper limit of the normal range), Increased alkaline phosphatase (>3 times the upper limit of the normal range), Hepatic failure Jaundice Skin and subcutaneous tissue disorders Common: Hyperhidrosis Uncommon: Eczema, Pruritus, Urticaria Rare: Erythematous rash, Face edema and angioedema Musculoskeletal and connective tissue disorders Common: Back pain General disorders and administration site conditions Common: Fatigue Renal and Urinary disorders Rare: Urinary retention
Known drug interactions: Potent CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin , moderate CYP1A2 inhibitors (e.g. propranolol, enoxacin ) .
- Sourced through authorised distributors and checked against batch and expiry on arrival
- Dispensed by a registered pharmacist from our DRAP-licensed branches
- Prescription verified by a pharmacist before your order is dispatched
- Same-day delivery in Karachi, Lahore and Islamabad on orders placed before 6pm
The recommended dose is 25 mg once daily taken orally at bedtime. After two weeks of treatment, if there is no improvement of symptoms, the dose may be increased to 50 mg once daily, i.e. two 25 mg tablets, taken together at bedtime. Or As directed by your physician.
Active ingredient: Agomelatine. Labelled strength: 25mg.
- Hypersensitivity to Agomelatine • Hepatic impairment (i.e. cirrhosis or active liver disease) or transaminases exceeding 3 times the upper limit of normal. • Concomitant use of potent CYP1A2 inhibitors (e.g. fluvoxamine, ciprofloxacin)
- Agomelatine should not be used for the treatment of major depressive episodes in elderly patients with dementia since the safety and efficacy of Agomelatine have not been established in these patients.
- Agomelatine should be used with caution in patients with a history of bipolar disorder, mania or hypomania and should be discontinued if a patient develops manic symptoms.
- Depression is associated with an increased risk of suicidal thoughts, self-harm and suicide (suicide-related events). This risk persists until significant remission occurs. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase in the early stages of recovery .
- Caution should be exercised when prescribing Agomelatine with moderate CYP1A2 inhibitors (e.g. propranolol, enoxacin) which may result in increased exposure of agomelatine.
Store this medicine at room temperature, away from direct light and heat.
Manufactured by Agoviz Laboratories (Pvt) Ltd.. Country of origin: United Arab Emirates.
4.0
Rated 4.0 out of 537 verified ratings
- 5★0%
- 4★75%
- 3★25%
- 2★0%
- 1★0%
- Adnan YousufVerified Purchase4 Aug 2026Rated 3.0 out of 5
Fine quality, wrong choice on my part — I should have asked the pharmacist first about the strength.
- Mehwish A.25 Jul 2026Rated 4.0 out of 5
Works as expected. Took about three weeks to notice a difference, which the product page had already told me to expect.
- Fatima S.Verified Purchase14 Jul 2026Rated 4.0 out of 5
Good value for the pack size. I compared prices across three sites before ordering.
- Ayesha K.Verified Purchase7 Jul 2026Rated 4.0 out of 5
Does the job, though the pack is smaller than I expected — worth checking the size before ordering.
Reviews are from verified Hope Pharmacy orders. We do not remove a review for being critical.
Frequently bought together
SearleAgoviz 25mg Tablets 14sRs. 2,135Rated 4.0 out of 5
StandpharmXiga 5mg Tablets 14sRs. 1,595Rated 4.5 out of 5
Martin DowAldactone Tablets 100mg 10sRs. 1,390Rated 4.5 out of 5
Bundle total
Rs. 5,120Rs. 5,740
Information on this site is for general guidance and is not a substitute for professional medical advice. Always consult your doctor or pharmacist.
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