Dermovate Oint 20gm

What it is used for: Eczema.

Indications as listed by the manufacturer: It is used to help reduce the redness and itchiness of certain skin problems. These skin problems include: • Frequently relapsing eczema • Psoriasis (thickened patches of inflamed, red skin, often covered by silvery scales), excluding widespread plaque psoriasis • Lichen planus (a skin disease that causes itchy, reddish-purple, flat-topped bumps on the wrists, forearms or lower legs) • Discoid lupus erythematosus (a disease of the skin most often affecting the face, ears and scalp causing scarring and increased sensitivity of the affected skin to sunlight) • Dermatitis and other skin conditions that have not responded to milder steroid creams or ointments .

How it works: Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.

Active ingredient: Clobetasol Propionate.

Reported side effects: Common (may affect up to 1 in 10 people) • a feeling of burning, pain, irritation or itching where the ointment is applied. Uncommon (may affect up to 1 in 100 people) • skin thinning, stretch marks may develop. • blood vessels under the surface of your skin may become more noticeable. Very Rare (may affect up to 1 in 10,000 people)Use of Dermovate for a long period of time, or use under an airtight dressing, may cause the following symptoms: • increased weight • moon face, rounding of the face • obesity • skin thinning • skin wrinkling • skin dryness • changes to the colour of your skin • increased body hair • hair loss/lack of hair growth/damaged looking hair.

Known drug interactions: Ritonavir and itraconazole

Adults : Apply sparingly once or twice daily for max four wk, then review. Children : Same as adult but review weekly. OR As directed by your physician.

Active ingredient: Clobetasol Propionate.

Store this medicine at room temperature, away from direct light and heat.

Manufactured by Dermovate Pharmaceuticals (Pvt) Ltd.. Country of origin: Pakistan.